Image de l'éditeur

Genome Stability and Human Diseases (Hardback)

Edité par Springer, Netherlands, 2010
ISBN 10: 9048134706 / ISBN 13: 9789048134700
Neuf(s) / Hardback / Quantité : 1
Vendeur The Book Depository US (London, Royaume-Uni)
Disponible auprès d'autres vendeurs
Afficher tous les  exemplaires de ce livre
Ajouter au panier
Prix conseillé :
Prix: EUR 245,23
Autre devise
Livraison : EUR 0
De Royaume-Uni vers Etats-Unis
Destinations, frais et délais

Mettre de côté

Au sujet du livre

Détails bibliographiques


Titre : Genome Stability and Human Diseases (...

Éditeur : Springer, Netherlands

Date d'édition : 2010

Reliure : Hardback

Etat du livre : New

Description :

Language: English . Brand New Book. Since the establishment of the DNA structure researchers have been highly interested in the molecular basis of the inheritance of genes and of genetic disorders. Scientific investigations of the last two decades have shown that, in addition to oncogenic viruses and signalling pathways alterations, genomic instability is important in the development of cancer. This view is supported by the findings that aneuploidy, which results from chromosome instability, is one of the hallmarks of cancer cells. Chromosomal instability also underpins our fundamental principles of understanding tumourigenesis: It thought that cancer arises from the sequential acquisition of genetic alterations in specific genes. In this hypothesis, these rare genetic events represent rate-limiting bottlenecks in the clonal evolution of a cancer, and pre-cancerous cells can evolve into neoplastic cells through the acquisition of somatic mutations. This book is written by international leading scientists in the field of genome stability. Chapters are devoted to genome stability and anti-cancer drug targets, histone modifications, chromatin factors, DNA repair, apoptosis and many other key areas of research. The chapters give insights into the newest development of the genome stability and human diseases and bring the current understanding of the mechanisms leading to chromosome instability and their potential for clinical impact to the reader. N° de réf. du libraire LIB9789048134700

A propos du livre :

Book ratings provided by GoodReads) :
0 note moyenne
(0 avis)

Synopsis :

Since the establishment of the DNA structure researchers have been highly interested in the molecular basis of the inheritance of genes and of genetic disorders. Scientific investigations of the last two decades have shown that, in addition to oncogenic viruses and signalling pathways alterations, genomic instability is important in the development of cancer. This view is supported by the findings that aneuploidy, which results from chromosome instability, is one of the hallmarks of cancer cells. Chromosomal instability also underpins our fundamental principles of understanding tumourigenesis: It thought that cancer arises from the sequential acquisition of genetic alterations in specific genes. In this hypothesis, these rare genetic events represent rate-limiting 'bottlenecks' in the clonal evolution of a cancer, and pre-cancerous cells can evolve into neoplastic cells through the acquisition of somatic mutations.

This book is written by international leading scientists in the field of genome stability. Chapters are devoted to genome stability and anti-cancer drug targets, histone modifications, chromatin factors, DNA repair, apoptosis and many other key areas of research. The chapters give insights into the newest development of the genome stability and human diseases and bring the current understanding of the mechanisms leading to chromosome instability and their potential for clinical impact to the reader.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Librairie et conditions de vente

Modes de paiement

Le libraire accepte les modes de paiement suivants :

  • American Express
  • Carte Bleue
  • EuroCard/MasterCard
  • Visa

[Chercher dans le catalogue du libraire]

[Afficher le catalogue du vendeur]

[Poser une question au libraire]

Libraire : The Book Depository US
Adresse : London, Royaume-Uni

Vendeur AbeBooks depuis : 10 septembre 2013
Evaluation du vendeur : Evaluation 5 étoiles

Conditions de vente :

All books are shipped in New condition promptly, we are happy to accept returns up to 30 days from purchase. Orders usually ship within 1-2 business days. Domestic Shipments are sent by Royal Mail, and International by Priority Airmail. We are happy to accept returns up to 30 days from purchase. Please contact the seller directly if you wish to return an order. Name of business : The Book Depository Ltd Form of legal entity : A Limited Company Business address: The Book Depository, 60 Holborn Vi...

[Pour plus d'information]

Conditions de livraison :

Orders usually ship within 1-2 business days. Domestic Shipments are sent by Royal Mail, and International by Priority Airmail. We are happy to accept returns up to 30 days from purchase. Please contact the seller directly if you wish to return an order.


Description de la librairie : Book Depository is an international bookseller. We ship our books to over 100 countries around the globe and we are always looking to add more countries to the list. We really, really love books and offer millions of titles, currently over 10 million of them, with this figure increasing daily. Living by our motto, 'Bookseller to the World', we focus on offering as many titles as possible to as many customers as possible. Most of our titles are dispatched within 2 business days of your order. Apart from publishers, distributors and wholesalers, we even list and supply books from other retailers! We hope you enjoy our selection and discover your new favorite book.