Gene Regulation: A Eukaryotic Perspective - Couverture souple

Latchman, David S.

Couverture souple

ISBN 10 : 0044452438 ISBN 13 : 9780044452430

Editeur : Kluwer Academic Publishers, 1990

Synopsis

"Gene Regulation" provides a view of gene control systems from a eukaryotic standpoint, and tries to redress the bias towards prokaryotic control models. The text explores a variety of regulational strategies and defines their functional significance to the organism as a whole. The opening chapters examine the possible processes and mechanisms by which genes could be controlled at different levels, and establish that the key control structures lie at the level of gene transcription. Further chapters continue with an examination of the various steps in transcriptional regulation and explain how events at the molecular level finally have their impact on the biology of the organism via the expression of a diversity of proteins. The final section takes a look at the role of malregulation of gene expression in causing human diseases, particularly in relation to certain forms of cancer. This book should appeal to a wide range of intermediate and advanced students of molecular biology, biochemistry, genetics and clinicians working in these areas.

A propos du livre

Présentation de l'éditeur

For this forth edition, the book has been updated thoroughly, with particular emphasis on modulation of chromatin structure by histone modifications/ remodelling complexes and the role of co-activators/ co-repressors. Methods used to analyse gene expression have also been given more attention, with a new section added on methods for examining DNA binding by transcription factors. Additionally, new sections have been added on coupling of transcription factors. Additionally, new sections have been added on coupling of transcription with post-transcriptional process and negatively acting sequence elements, which are of increasing prominence.

Présentation de l'éditeur

Gene regulation is an essential process in the development and maintenance of a healthy body, and as such, is a central focus in both basic science and medical research.  Gene Regulation, Fifth Edition provides the student and researcher with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview.

Détails de l'édition

• Éditeur: Kluwer Academic Publishers
• Date d'édition: 1990
• Langue: anglais
• ISBN 10: 0044452438
• ISBN 13: 9780044452430
• Reliure: Broché
• Nombre de pages: 220
• Coordonnées du fabricant: non disponible
• Personne responsable: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Allemagne