Osteoimmunology: Interactions of the Immune and Skeletal Systems

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9780128005712: Osteoimmunology: Interactions of the Immune and Skeletal Systems
Présentation de l'éditeur :

Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology.

This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics.

Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget’s disease, the genetics of bone disease, and bone cancer metastasis.



  • Explains the intricate interaction between the immune system and bone
  • Features detailed discussions of the key cellular and molecular mechanisms governing the homeostasis of the individual systems
  • Facilitates greater understanding of osteoimmunologic networks, their environments, and how this understanding leads to better treatments for human diseases involving both systems

Biographie de l'auteur :

Dr. Lorenzo is Professor of medicine in the Division of Endocrinology and Metabolism and Director of Bone Biology Research at the University of Connecticut Health Center. He is a nationally renowned expert on bone remodeling and its effect on bone health.

Dr. Horowitz is Professor of Orthopaedics and Rehabilitation at the Yale University School of Medicine. His research interests include the interactions between the skeletal, immune, and hematopoietic systems as they relate to normal and pathologic bone remodeling.

Dr. Choi is Professor of Pathology and Laboratory Medicine, University of Pennsylvania; Investigator, The Leonard and Marilyn Abramson Family Cancer Research Institute, Philadelphia, PA.

Dr. Takayanagi is Professor in the Department of Cell Signaling, Tokyo Medical and Dental University. His group studies the mechanism of bone destruction in rheumatoid arthritis, which focuses on the regulation of osteoclasts by T cells. This interdisciplinary field, osteoimmunology, covers various research on shared mechanisms and interactions between immune and bone systems.

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Joseph Lorenzo, Mark Horowitz, Yongwon Choi, Hiroshi Takayanagi, Georg Schett
Edité par Academic Press Inc 2015-09-01 (2015)
ISBN 10 : 0128005718 ISBN 13 : 9780128005712
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Description du livre Academic Press Inc 2015-09-01, 2015. Hardcover. État : New. N° de réf. du libraire NU-ELS-00006739

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Edité par Elsevier Science Publishing Co Inc, United States (2015)
ISBN 10 : 0128005718 ISBN 13 : 9780128005712
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Description du livre Elsevier Science Publishing Co Inc, United States, 2015. Hardback. État : New. 2nd Revised edition. 276 x 216 mm. Language: English . Brand New Book. Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget s disease, the genetics of bone disease, and bone cancer metastasis. N° de réf. du libraire AAU9780128005712

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Edité par Elsevier Science Publishing Co Inc, United States (2015)
ISBN 10 : 0128005718 ISBN 13 : 9780128005712
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The Book Depository US
(London, Royaume-Uni)
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Description du livre Elsevier Science Publishing Co Inc, United States, 2015. Hardback. État : New. 2nd Revised edition. 276 x 216 mm. Language: English . Brand New Book. Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget s disease, the genetics of bone disease, and bone cancer metastasis. N° de réf. du libraire AAU9780128005712

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Edité par Academic Press (2015)
ISBN 10 : 0128005718 ISBN 13 : 9780128005712
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Description du livre Academic Press, 2015. État : New. Editor(s): Lorenzo, Joseph; Horowitz, Mark; Choi, Yongwon; Takayanagi, Hiroshi; Schett, Georg. Num Pages: 376 pages. BIC Classification: MJCM. Category: (P) Professional & Vocational. Dimension: 276 x 216 x 23. Weight in Grams: 1270. . 2015. 2nd Edition. Hardcover. . . . . . N° de réf. du libraire V9780128005712

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Lorenzo, Joseph (EDT)/ Horowitz, Mark (EDT)/ Choi, Yongwon (EDT)/ Takayanagi, Hiroshi (EDT)/ Schett, Georg (EDT)
Edité par Elsevier Science Publishing Co Inc 2015-10-05, San Diego (2015)
ISBN 10 : 0128005718 ISBN 13 : 9780128005712
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Blackwell's
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Description du livre Elsevier Science Publishing Co Inc 2015-10-05, San Diego, 2015. hardback. État : New. N° de réf. du libraire 9780128005712

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Edité par Academic Press
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Kennys Bookstore
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Description du livre Academic Press. État : New. Editor(s): Lorenzo, Joseph; Horowitz, Mark; Choi, Yongwon; Takayanagi, Hiroshi; Schett, Georg. Num Pages: 376 pages. BIC Classification: MJCM. Category: (P) Professional & Vocational. Dimension: 276 x 216 x 23. Weight in Grams: 1270. . 2015. 2nd Edition. Hardcover. . . . . Books ship from the US and Ireland. N° de réf. du libraire V9780128005712

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Joseph Lorenzo
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Description du livre Hardback. État : New. Not Signed; Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as t. book. N° de réf. du libraire ria9780128005712_rkm

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ISBN 10 : 0128005718 ISBN 13 : 9780128005712
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LORENZO, JOSEPH; HOROWITZ, MARK; CHOI, YONGWON; TAKAYANAGI, HIROSHI; SCHETT, GEORG
Edité par Academic Press (2015)
ISBN 10 : 0128005718 ISBN 13 : 9780128005712
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Description du livre Academic Press, 2015. Hardback. État : NEW. 9780128005712 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. N° de réf. du libraire HTANDREE0954757

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LORENZO, JOSEPH; HOROWITZ, MARK; CHOI, YONGWON; TAKAYANAGI, HIROSHI; SCHETT, GEORG
Edité par Academic Press (2015)
ISBN 10 : 0128005718 ISBN 13 : 9780128005712
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Herb Tandree Philosophy Books
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Description du livre Academic Press, 2015. Hardback. État : NEW. 9780128005712 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. N° de réf. du libraire HTANDREE01199665

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