Concepts of Genetics - Couverture rigide

Klug, William S.; Cummings, Michael R.

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Couverture rigide

ISBN 10 : 0130816264 ISBN 13 : 9780130816269

Editeur : Benjamin Cummings, 1999

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Book by Klug William S Cummings Michael R

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Biographie de l'auteur :

William S. Klug is currently Professor of Biology at The College of New Jersey (formerly Trenton State College) in Ewing, New Jersey. He served as Chairman of the Biology Department for 17 years, a position to which he was first elected in 1974. He received his B.A. degree in Biology from Wabash College in Crawfordsville, Indiana and his Ph.D. from Northwestern University in Evanston, Illinois. Prior to coming to Trenton State College, he returned to Wabash College as an Assistant Professor, where he first taught genetics as well as general biology and electron microscopy. His research interests have involved ultra-structural and molecular genetic studies of oogenesis in Drosophila. He has taught the genetics course as well as the senior capstone seminar course in human and molecular genetics to undergraduate Biology majors for each of the last 33 years. He was the recent recipient of the first annual teaching award given at The College of New Jersey as the faculty member who most challenges students to meet high standards.

Michael R. Cummings is currently Associate Professor in the Department of Biological Sciences and in the Department of Molecular Genetics at the University of Illinois at Chicago. He has also served on the faculty at Northwestern University and Florida State University. He received his B.A. from St. Mary's College in Winona, Minnesota, and his M.S. and Ph.D. from Northwestern University in Evanston, Illinois. He has also written textbooks in 'human genetics and general biology for non-majors. His research interests center on the molecular organization and physical mapping of human acrocentric chromosomes. At the undergraduate level, he teaches courses in Mendelian genetics, human genetics, and general biology for non-majors. He has received numerous teaching awards given by the university and by student organizations.

Quatri�me de couverture :

Geneticists have long been intrigued as to how several meters of DNA are packed into the eukaryotic nucleus. The discovery of nucleosomes has provided significant insights into this question.

The cover illustration depicts the X-ray crystal structure of the nucleosome core particle at a resolution of 2.8 �A. The nucleosome is an integral part of the structure of eukaryotic chromatin. The double-helical ribbon represents 146 base pairs of DNA surrounding four pairs of histone proteins. The nucleosome core particle is repeated over and over in the chromatin fiber and is the principal packaging unit of DNA in the nucleus.

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