Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs defines biotechnology from the perspective of pharmaceuticals. The first section focuses on the process of transforming a biologic macromolecule into a therapeutic agent, while the second section provides a brief overview of each class of macromolecule with respect to physiological role and clinical application. Additional detail is also provided in the second section for each FDA approved, recombinantly derived biopharmaceutical for each category of macromolecule. The final section looks to the future and the new advances that will enhance our ability to develop new macromolecules into effective biopharmaceuticals. This last section discusses various drug delivery strategies while also describing gene and cell therapy strategies.
"The authors of this book should be congratulated for making available to scientists, healthcare professionals, and students all of this information in a single volume. The chapters are written in a manner that is understandable to non-experts in the field. By utilizing this book as a source of new information to increase their breadth of knowledge, scientists currently in the industry will become more effective contributors to the drug discovery and development efforts of their companies." (from the Foreword by Ronald T. Borchardt, University of Kansas)From the Back Cover :
The study and manipulation of life forms on the molecular level continues to set the pace in modern science and medicine. Biotechnology and Biopharmaceuticals represents a unique, textual combination of these two dynamic disciplines, focusing on the role biotechnology plays in the discovery and development of therapeutic drugs.
The first of the book’s three sections focuses on the process of transforming a macromolecule into a therapeutic agent; the second provides a brief overview of each class of macromolecule with respect to physiological role and clinical application. The second section also provides additional detail for each FDA approved biopharmaceutical. The final section looks to new advances that will enhance our ability to develop new macromolecules into effective biopharmaceuticals. Biotechnology and Biopharmaceuticals also:
Biotechnology and Biopharmaceuticals provides an ideal resource for graduate students and undergraduates in colleges of pharmacy and health sciences, for pharmaceutical and biomedical scientists in academia and industry, and for clinical pharmacists and medical center—based clinicians.
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