Probabilistic Boolean Networks: The Modeling and Control of Gene Regulatory Networks

Note moyenne 4
( 1 avis fournis par Goodreads )
 
9780898716924: Probabilistic Boolean Networks: The Modeling and Control of Gene Regulatory Networks

This is the first comprehensive treatment of probabilistic Boolean networks (PBNs), an important model class for studying genetic regulatory networks. This book covers basic model properties, including the relationships between network structure and dynamics, steady-state analysis, and relationships to other model classes. It also discusses the inference of model parameters from experimental data and control strategies for driving network behavior towards desirable states.

The PBN model is well suited to serve as a mathematical framework to study basic issues dealing with systems-based genomics, specifically, the relevant aspects of stochastic, nonlinear dynamical systems. The book builds a rigorous mathematical foundation for exploring these issues, which include long-run dynamical properties and how these correspond to therapeutic goals; the effect of complexity on model inference and the resulting consequences of model uncertainty; altering network dynamics via structural intervention, such as perturbing gene logic; optimal control of regulatory networks over time; limitations imposed on the ability to achieve optimal control owing to model complexity; and the effects of asynchronicity.

The authors attempt to unify different strands of current research and address emerging issues such as constrained control, greedy control, and asynchronicity.

Audience: Researchers in mathematics, computer science, and engineering are exposed to important applications in systems biology and presented with ample opportunities for developing new approaches and methods. The book is also appropriate for advanced undergraduates, graduate students, and scientists working in the fields of computational biology, genomic signal processing, control and systems theory, and computer science.

Contents: Preface; Chapter 1: Boolean Networks; Chapter 2; Structure and Dynamics of Probabilistic Boolean Networks; Chapter 3: Inference of Model Structure; Chapter 4: Structural Intervention; Chapter 5: External Control; Chapter 6: Asynchronous Networks; Bibliography; Index

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Book Description :

This book is the first comprehensive treatment of probabilistic Boolean networks, an important model class for studying genetic regulatory networks. The PBN model is well-suited to serve as a mathematical framework to study basic issues of systems-based genomics and this book builds a rigorous mathematical foundation for exploring these issues.

About the Author :

Ilya Shmulevich is a professor at the Institute for Systems Biology, Seattle, WA. Edward R. Dougherty is a professor and director of the Genomic Signal Processing Laboratory at Texas A&M University, College Station, TX. He is also co-director of the Computational Biology Division of the Translational Genomics Research Institute, Phoenix, AZ.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Meilleurs résultats de recherche sur AbeBooks

1.

Ilya Shmulevich, Edward R. Dougherty
Edité par SIAM-Society for Industrial and Applied Mathematics (2009)
ISBN 10 : 0898716926 ISBN 13 : 9780898716924
Neuf(s) Paperback Quantité : 1
Vendeur
Ergodebooks
(RICHMOND, TX, Etats-Unis)
Evaluation vendeur
[?]

Description du livre SIAM-Society for Industrial and Applied Mathematics, 2009. Paperback. État : New. N° de réf. du libraire DADAX0898716926

Plus d'informations sur ce vendeur | Poser une question au libraire

Acheter neuf
EUR 50,37
Autre devise

Ajouter au panier

Frais de port : EUR 3,42
Vers Etats-Unis
Destinations, frais et délais

2.

Ilya Shmulevich; Edward R. Dougherty
Edité par SIAM-Society for Industrial and Applied Mathematics (2009)
ISBN 10 : 0898716926 ISBN 13 : 9780898716924
Neuf(s) Paperback Quantité : 1
Vendeur
Irish Booksellers
(Rumford, ME, Etats-Unis)
Evaluation vendeur
[?]

Description du livre SIAM-Society for Industrial and Applied Mathematics, 2009. Paperback. État : New. book. N° de réf. du libraire 0898716926

Plus d'informations sur ce vendeur | Poser une question au libraire

Acheter neuf
EUR 54,33
Autre devise

Ajouter au panier

Frais de port : Gratuit
Vers Etats-Unis
Destinations, frais et délais

3.

Ilya Shmulevich, Edward R. Dougherty
Edité par Society for Industrial Applied Mathematics,U.S., United States (2010)
ISBN 10 : 0898716926 ISBN 13 : 9780898716924
Neuf(s) Paperback Quantité : 10
Vendeur
The Book Depository
(London, Royaume-Uni)
Evaluation vendeur
[?]

Description du livre Society for Industrial Applied Mathematics,U.S., United States, 2010. Paperback. État : New. New.. Language: English . Brand New Book. This is the first comprehensive treatment of probabilistic Boolean networks (PBNs), an important model class for studying genetic regulatory networks. This book covers basic model properties, including the relationships between network structure and dynamics, steady-state analysis, and relationships to other model classes. It also discusses the inference of model parameters from experimental data and control strategies for driving network behavior towards desirable states. The PBN model is well suited to serve as a mathematical framework to study basic issues dealing with systems-based genomics, specifically, the relevant aspects of stochastic, nonlinear dynamical systems.The book builds a rigorous mathematical foundation for exploring these issues, which include long-run dynamical properties and how these correspond to therapeutic goals; the effect of complexity on model inference and the resulting consequences of model uncertainty; altering network dynamics via structural intervention, such as perturbing gene logic; optimal control of regulatory networks over time; limitations imposed on the ability to achieve optimal control owing to model complexity; and the effects of asynchronicity. The authors attempt to unify different strands of current research and address emerging issues such as constrained control, greedy control, and asynchronicity. N° de réf. du libraire AAN9780898716924

Plus d'informations sur ce vendeur | Poser une question au libraire

Acheter neuf
EUR 62,64
Autre devise

Ajouter au panier

Frais de port : Gratuit
De Royaume-Uni vers Etats-Unis
Destinations, frais et délais

4.

Ilya Shmulevich, Edward R. Dougherty
Edité par Society for Industrial Applied Mathematics,U.S., United States (2010)
ISBN 10 : 0898716926 ISBN 13 : 9780898716924
Neuf(s) Paperback Quantité : 10
Vendeur
The Book Depository US
(London, Royaume-Uni)
Evaluation vendeur
[?]

Description du livre Society for Industrial Applied Mathematics,U.S., United States, 2010. Paperback. État : New. New.. Language: English . Brand New Book. This is the first comprehensive treatment of probabilistic Boolean networks (PBNs), an important model class for studying genetic regulatory networks. This book covers basic model properties, including the relationships between network structure and dynamics, steady-state analysis, and relationships to other model classes. It also discusses the inference of model parameters from experimental data and control strategies for driving network behavior towards desirable states. The PBN model is well suited to serve as a mathematical framework to study basic issues dealing with systems-based genomics, specifically, the relevant aspects of stochastic, nonlinear dynamical systems.The book builds a rigorous mathematical foundation for exploring these issues, which include long-run dynamical properties and how these correspond to therapeutic goals; the effect of complexity on model inference and the resulting consequences of model uncertainty; altering network dynamics via structural intervention, such as perturbing gene logic; optimal control of regulatory networks over time; limitations imposed on the ability to achieve optimal control owing to model complexity; and the effects of asynchronicity. The authors attempt to unify different strands of current research and address emerging issues such as constrained control, greedy control, and asynchronicity. N° de réf. du libraire AAN9780898716924

Plus d'informations sur ce vendeur | Poser une question au libraire

Acheter neuf
EUR 62,96
Autre devise

Ajouter au panier

Frais de port : Gratuit
De Royaume-Uni vers Etats-Unis
Destinations, frais et délais

5.

Shmulevich, Ilya
Edité par Society for Industrial and Applied Mathematics (2010)
ISBN 10 : 0898716926 ISBN 13 : 9780898716924
Neuf(s) Quantité : 10
Vendeur
Books2Anywhere
(Fairford, GLOS, Royaume-Uni)
Evaluation vendeur
[?]

Description du livre Society for Industrial and Applied Mathematics, 2010. PAP. État : New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. N° de réf. du libraire CE-9780898716924

Plus d'informations sur ce vendeur | Poser une question au libraire

Acheter neuf
EUR 54,07
Autre devise

Ajouter au panier

Frais de port : EUR 10,03
De Royaume-Uni vers Etats-Unis
Destinations, frais et délais

6.

Ilya Shmulevich, Edward R. Dougherty
Edité par Society for Industrial & Applied Mathematics,U.S.
ISBN 10 : 0898716926 ISBN 13 : 9780898716924
Neuf(s) Paperback Quantité : 10
Vendeur
THE SAINT BOOKSTORE
(Southport, Royaume-Uni)
Evaluation vendeur
[?]

Description du livre Society for Industrial & Applied Mathematics,U.S. Paperback. État : new. BRAND NEW, Probabilistic Boolean Networks: The Modeling and Control of Gene Regulatory Networks, Ilya Shmulevich, Edward R. Dougherty, The first comprehensive treatment of probabilistic Boolean networks (an important model class for studying genetic regulatory networks), this book covers basic model properties, including the relationships between network structure and dynamics, steady-state analysis, and relationships to other model classes. As the PBN model can serve as a mathematical framework for studying the basic issues of systems-based genomics, the book builds a rigorous mathematical foundation for exploring these issues, which include long-run dynamical properties and how these correspond to therapeutic goals; the effect of complexity on model inference and the resulting consequences of model uncertainty; altering network dynamics via structural intervention, such as perturbing gene logic; optimal control of regulatory networks over time; limitations imposed on the ability to achieve optimal control owing to model complexity; and the effects of asynchronicity. The authors unify different strands of current research and address emerging issues such as constrained control, greedy control, and asynchronicity. N° de réf. du libraire B9780898716924

Plus d'informations sur ce vendeur | Poser une question au libraire

Acheter neuf
EUR 57,45
Autre devise

Ajouter au panier

Frais de port : EUR 7,74
De Royaume-Uni vers Etats-Unis
Destinations, frais et délais

7.

ILYA SHMULEVICH , EDWARD R. DOUGHERTY
Edité par Soc Industrial Applied Maths (2009)
ISBN 10 : 0898716926 ISBN 13 : 9780898716924
Neuf(s) Paperback Quantité : 10
Vendeur
Herb Tandree Philosophy Books
(Stroud, GLOS, Royaume-Uni)
Evaluation vendeur
[?]

Description du livre Soc Industrial Applied Maths, 2009. Paperback. État : NEW. 9780898716924 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. N° de réf. du libraire HTANDREE0484215

Plus d'informations sur ce vendeur | Poser une question au libraire

Acheter neuf
EUR 72,82
Autre devise

Ajouter au panier

Frais de port : EUR 8,91
De Royaume-Uni vers Etats-Unis
Destinations, frais et délais

8.

Shmulevich, Ilya/ Dougherty, Edward R.
Edité par Society for Industrial & Applied (2010)
ISBN 10 : 0898716926 ISBN 13 : 9780898716924
Neuf(s) Paperback Quantité : 2
Vendeur
Revaluation Books
(Exeter, Royaume-Uni)
Evaluation vendeur
[?]

Description du livre Society for Industrial & Applied, 2010. Paperback. État : Brand New. 267 pages. 9.75x7.00x0.75 inches. In Stock. N° de réf. du libraire __0898716926

Plus d'informations sur ce vendeur | Poser une question au libraire

Acheter neuf
EUR 79,33
Autre devise

Ajouter au panier

Frais de port : EUR 6,68
De Royaume-Uni vers Etats-Unis
Destinations, frais et délais

9.

Ilya Shmulevich; Edward R. Dougherty
ISBN 10 : 0898716926 ISBN 13 : 9780898716924
Neuf(s) Quantité : 2
Vendeur
BWB
(Valley Stream, NY, Etats-Unis)
Evaluation vendeur
[?]

Description du livre État : New. Depending on your location, this item may ship from the US or UK. N° de réf. du libraire 97808987169240000000

Plus d'informations sur ce vendeur | Poser une question au libraire

Acheter neuf
EUR 102,44
Autre devise

Ajouter au panier

Frais de port : Gratuit
Vers Etats-Unis
Destinations, frais et délais