Articles liés à p53: The Gene that Cracked the Cancer Code
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All of us have lurking in our DNA a most remarkable gene, which has a crucial job - it protects us from cancer. Known simply as p53, this gene constantly scans our cells to ensure that they grow and divide without mishap, as part of the routine maintenance of our bodies. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, summoning a repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control, p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or prevented from functioning normally. Perhaps unsurprisingly, p53 is the most studied single gene in history. This book tells the story of medical science's mission to unravel the mysteries of this crucial gene, and to get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, p53: The Gene that Cracked the Cancer Code reveals the fascination of the quest for scientific understanding, as well as the huge excitement of the chase for new cures - the hype, the enthusiasm, the lost opportunities, the blind alleys, and the thrilling breakthroughs. And as the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms begins to take off at last, p53 remains at the cutting edge. This timely tale of scientific discovery highlights the tremendous recent advances made in our understanding of cancer, a disease that affects more than one in three of us at some point in our lives.
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Présentation de l'éditeur :
All of us have lurking in our DNA a most remarkable gene. Its job is straightforward to protect us from cancer. This gene known simply as p53 constantly scans our cells to ensure that they grow and divide without mishap, as part of the routine maintenance of our bodies. If a cell makes a mistake in copying its DNA as part of its process of division, p53 stops it in its tracks, sending in the repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged and malfunctioning. Not surprisingly, p53 is the most studied gene in history.
This enormously important gene has teased the minds of some of the most colourful and ambitious scientists around the world. These characters populate Sue Armstrong s book p53: The Gene that Cracked the Cancer Code, the story of medical science s mission to unravel the mysteries of this gene and to get to the heart of what happens in our cells when they turn cancerous. p53: The Gene that Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures the hype, the lost opportunities, the blind alleys and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient s symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
Biographie de l'auteur :
This enormously important gene has teased the minds of some of the most colourful and ambitious scientists around the world. These characters populate Sue Armstrong s book p53: The Gene that Cracked the Cancer Code, the story of medical science s mission to unravel the mysteries of this gene and to get to the heart of what happens in our cells when they turn cancerous. p53: The Gene that Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures the hype, the lost opportunities, the blind alleys and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient s symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
Sue Armstrong is a science writer and broadcaster based in Edinburgh. She has worked for a variety of media organisations, including New Scientist, and since the 1980s has undertaken regular assignments for the World Health Organization (WHO) and UNAIDS, writing about women's health issues and the AIDS pandemic, among many other topics, and reporting from the frontline in countries as diverse as Haiti, Papua New Guinea, Uganda, Thailand, Namibia and Serbia. Sue has been involved, as presenter, writer and researcher, in several major medical documentaries for BBC Radio 4.
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- ÉditeurBloomsbury Sigma
- Date d'édition2014
- ISBN 10 1472913205
- ISBN 13 9781472913203
- ReliureBroché
- Nombre de pages288
- Evaluation vendeur
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