Articles liés à The Cancer Degradome: Proteases and Cancer Biology
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- ÉditeurSpringer-Verlag New York Inc.
- Date d'édition2016
- ISBN 10 149393886X
- ISBN 13 9781493938865
- ReliureBroché
- Nombre de pages926
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The Cancer Degradome
Edité par
Springer New York
(2016)
ISBN 10 : 149393886X
ISBN 13 : 9781493938865
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Description du livre Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. In the context of the battle against cancer, the Degradome is important in three principal areas:Cellular proteases and their inhibitors are components of the molecular machinery of malignancy, and thus are attractive as therapeutic. N° de réf. du vendeur 447955406
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The Cancer Degradome : Proteases and Cancer Biology
Edité par
Springer
(2016)
ISBN 10 : 149393886X
ISBN 13 : 9781493938865
Neuf
Couverture souple
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Description du livre Etat : New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. N° de réf. du vendeur ria9781493938865_lsuk
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The Cancer Degradome
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Springer New York Aug 2016
(2016)
ISBN 10 : 149393886X
ISBN 13 : 9781493938865
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Description du livre Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Proteases that act in the extracellular environment have been historically associated with tumorigenesis and metastasis by virtue of their ability to carry out 'path-clearing' for cancer cells. In the past few years it has become clear that they also shape the pericellular signaling environment, with profound consequences for cell fate and phenotype in both normal development and disease states. The repertoire of proteases that cells and tissues coordinately regulate in order to modulate their local environment is the DEGRADOME - which in humans is represented by at least 569 proteases in five catalytic classes. ' The Cancer Degradome: Proteases in Cancer Biology ' , edited by Dylan Edwards, Francesco Blasi, Gunilla-Høyer-Hansen and Bonnie Sloane, covers recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; how protease activity can be imaged both in vitro and in vivo ; how gene knockout mice have improved our knowledge of the roles of proteases in cancer; the links that have emerged between proteolysis and cell signaling; how the Degradome can be a useful source of diagnostic and prognostic markers; and finally new approaches to target proteolysis for therapy. 984 pp. Englisch. N° de réf. du vendeur 9781493938865
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The Cancer Degradome : Proteases and Cancer Biology
Edité par
Springer New York
(2016)
ISBN 10 : 149393886X
ISBN 13 : 9781493938865
Neuf
Taschenbuch
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Description du livre Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Proteases that act in the extracellular environment have been historically associated with tumorigenesis and metastasis by virtue of their ability to carry out 'path-clearing' for cancer cells. In the past few years it has become clear that they also shape the pericellular signaling environment, with profound consequences for cell fate and phenotype in both normal development and disease states. The repertoire of proteases that cells and tissues coordinately regulate in order to modulate their local environment is the DEGRADOME - which in humans is represented by at least 569 proteases in five catalytic classes. ' The Cancer Degradome: Proteases in Cancer Biology ' , edited by Dylan Edwards, Francesco Blasi, Gunilla-Høyer-Hansen and Bonnie Sloane, covers recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; how protease activity can be imaged both in vitro and in vivo ; how gene knockout mice have improved our knowledge of the roles of proteases in cancer; the links that have emerged between proteolysis and cell signaling; how the Degradome can be a useful source of diagnostic and prognostic markers; and finally new approaches to target proteolysis for therapy. N° de réf. du vendeur 9781493938865
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The Cancer Degradome: Proteases and Cancer Biology [Paperback ]
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Springer
(2016)
ISBN 10 : 149393886X
ISBN 13 : 9781493938865
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Description du livre Soft Cover. Etat : new. N° de réf. du vendeur 9781493938865
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