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9781584880271: Introduction to Statistical Methods for Clinical Trials

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ISBN 10 : 1584880279 ISBN 13 : 9781584880271

Editeur : Chapman and Hall/CRC, 2007

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This text provides a solid understanding of the various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. It covers basic experimental design, sample size, randomization procedures, interim and survival analyses, quality of life assessment, and longitudinal methods. The book describes all phases of a clinical trial and explores the advantages of and objections to the intent-to-treat principle as well as its implementation. With exercises at the end of most chapters, it also illustrates methods using examples with real data from a variety of disease areas, including heart and lung diseases, cancer, and AIDS.

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Thomas D. Cook, David L. DeMets

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�diteur: Chapman and Hall/CRC
Date d'�dition: 2007
Langue: anglais
ISBN 10: 1584880279
ISBN 13: 9781584880271
Reliure: Reli�
Num�ro d'�dition: 1
Nombre de pages: 464
�diteur: Cook Thomas D., Zidek Jim, Carlin Bradley. P., DeMets David L., Tanner Martin A., Faraway Julian J.
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Introduction to Statistical Methods for Clinical Trials (Chapman & Hall/CRC Texts in Statistical Science)

Edit� par Chapman and Hall/CRC, 2007

ISBN 10 : 1584880279 ISBN 13 : 9781584880271

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Etat : good. All pages and cover are intact including the dust cover, if applicable . Spine may show signs of wear. Pages may include limited notes and highlighting. May include "From the library of" labels. Shrink wrap, dust covers, or boxed set case may be missing. Item may be missing bundled media. N� de r�f. du vendeur MINV.1584880279.G

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Introduction to Statistical Methods for Clinical Trials (Chapman & Hall/CRC Texts in Statistical Science)

Edit� par Chapman and Hall/CRC, 2007

ISBN 10 : 1584880279 ISBN 13 : 9781584880271

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Introduction to Statistical Methods for Clinical Trials

Cook, Thomas D. (EDT); Demets, David L. (EDT)

Edit� par Chapman and Hall/CRC, 2007

ISBN 10 : 1584880279 ISBN 13 : 9781584880271

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Introduction to Statistical Methods for Clinical Trials (Hardcover)

Thomas D. Cook

Edit� par Taylor & Francis Inc, 2007

ISBN 10 : 1584880279 ISBN 13 : 9781584880271

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Hardcover. Etat : new. Hardcover. Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial.After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals. Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in the design, conduct, and analysis of clinical trials. Clinical trials have taken a prominent role in the research and approval of drugs. This text offers a summary of statistical design, including cross-over designs, sample size estimation, sequential methods for interim analyses, survival analysis, and repeated measures. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. N� de r�f. du vendeur 9781584880271

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Introduction to Statistical Methods for Clinical Trials (Chapman & Hall/CRC Texts in Statistical Science)

Thomas D. Cook, David L. DeMets

Edit� par Chapman and Hall/CRC 2007-11-19, 2007

ISBN 10 : 1584880279 ISBN 13 : 9781584880271

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Introduction to Statistical Methods for Clinical Trials (Chapman & Hall/CRC Texts in Statistical Science)

Cook, Thomas D. [Editor]; DeMets, David L. [Editor];

Edit� par Routledge, 2007

ISBN 10 : 1584880279 ISBN 13 : 9781584880271

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Introduction to Statistical Methods for Clinical Trials

Thomas D. Cook

Edit� par CRC Press, 2007

ISBN 10 : 1584880279 ISBN 13 : 9781584880271

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Introduction to Statistical Methods for Clinical Trials

Thomas D. Cook

Edit� par CRC Press, 2007

ISBN 10 : 1584880279 ISBN 13 : 9781584880271

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Introduction to Statistical Methods for Clinical Trials

Cook, Thomas D. (EDT); Demets, David L. (EDT)

Edit� par Chapman and Hall/CRC, 2007

ISBN 10 : 1584880279 ISBN 13 : 9781584880271

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Introduction to Statistical Methods for Clinical Trials

Cook, Thomas D. (EDT); Demets, David L. (EDT)

Edit� par Chapman and Hall/CRC, 2007

ISBN 10 : 1584880279 ISBN 13 : 9781584880271

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