Description du livre Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. First book that covers the expertise from systems biology and pharmacodynamics researchers in one placeOutlines how systems pharmacology should reduce the high attrition in the drug development pipelineAll case studie. N� de r�f. du vendeur 385706164

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Systems Pharmacology and Pharmacodynamics (AAPS Advances in the Pharmaceutical Sciences Series, 23)

Edit� par Springer (2018)

ISBN 10 : 3319830740 ISBN 13 : 9783319830742

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Description du livre Etat : New. N� de r�f. du vendeur ABLIING23Mar3113020108638

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Systems Pharmacology and Pharmacodynamics

Holly H. C. Kimko

Edit� par Springer International Publishing Jul 2018 (2018)

ISBN 10 : 3319830740 ISBN 13 : 9783319830742

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Description du livre Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -While systems biology and pharmacodynamics have evolved in parallel,there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new disciplinethat is theinterface between these two methods. This book is the first tocover the expertise from systems biology and pharmacodynamics researchers, describing how systems pharmacology may be developed and refined further to show practical applications in drug development. There is a growing awareness that pharmaceutical companies should reduce the high attrition in the pipeline due to insufficient efficacy or toxicity found inproof-of-concept and/or PhaseII studies. Systems Pharmacology and Pharmacodynamicsdiscusses theframework for integrating information obtained fromunderstanding physiological/pathological pathways (normal body function system vs. perturbed system due to disease) and pharmacological targetsin order to predict clinical efficacy and adverse events through iterations between mathematical modeling and experimentation. 528 pp. Englisch. N� de r�f. du vendeur 9783319830742

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Systems Pharmacology and Pharmacodynamics

Holly H. C. Kimko

Edit� par Springer International Publishing (2018)

ISBN 10 : 3319830740 ISBN 13 : 9783319830742

Neuf Taschenbuch Quantit� disponible : 1

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AHA-BUCH GmbH
(Einbeck, Allemagne)

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Description du livre Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - While systems biology and pharmacodynamics have evolved in parallel,there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new disciplinethat is theinterface between these two methods. This book is the first tocover the expertise from systems biology and pharmacodynamics researchers, describing how systems pharmacology may be developed and refined further to show practical applications in drug development. There is a growing awareness that pharmaceutical companies should reduce the high attrition in the pipeline due to insufficient efficacy or toxicity found inproof-of-concept and/or PhaseII studies. Systems Pharmacology and Pharmacodynamicsdiscusses theframework for integrating information obtained fromunderstanding physiological/pathological pathways (normal body function system vs. perturbed system due to disease) and pharmacological targetsin order to predict clinical efficacy and adverse events through iterations between mathematical modeling and experimentation. N� de r�f. du vendeur 9783319830742

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