A-Hydroxy Acids in Enantioselective Syntheses - Couverture souple

Couverture souple

ISBN 10 : 3527290931 ISBN 13 : 9783527290932

Editeur : Wiley-VCH Verlag GmbH, 1997

A propos du livre

Quatrième de couverture

Gary M. Coppola Herbert F. Schuster –Hydroxy Acids in Enantioselective Syntheses An ideal synthesis starts with readily accessible reagents and yields the target molecules in high optical purity. The naturally available –hydroxy acids, lactic, malic, mandelic and tartaric acids, provide the chemist with chiral building blocks for the introduction of one or more asymmetric centers into an organic molecule. This book not only supplies a comprehensive discussion of useful reactions but also demonstrates how complex molecules can have their origin in simple, readily accessible chirally pure starting materials. The authors, both practicing medicinal research chemists, aim at providing information for the design and synthesis of chiral molecules. A particularly attractive feature of this text is the excellent schemes used to illustrate the crucial transformations. All structures are represented in their absolute stereochemistry. Mechanisms as well as insights into the execution of a synthetic pathway are discussed concisely, with a focus on practical aspects. The authors have drawn on their years of writing experience to supply graduate students, research chemists and teachers alike with a gold mine of useful chemistry. Every synthetic chemist will want to have this invaluable resource at his or her disposal.

Présentation de l'éditeur

Attention synthetic chemist!

Chiral alpha–hydroxy acids available from nature′s chiral pool serve as starting materials in a wide variety of enantioselective conversions leading to commercially important products. This monograph, a stimulating source of ideas and an essential reference work for research chemists, focuses on the well–known lactic, mandelic, malic, and tartaric acids.

Well–chosen examples show how chiral centers inherent in these simple compounds can be used to control the introduction of further stereogenic centers. Readers can directly apply new transformations in their own work since reaction conditions are given in handy tables.

Détails de l'édition

• Éditeur: Wiley-VCH Verlag GmbH
• Date d'édition: 1997
• Langue: anglais
• ISBN 10: 3527290931
• ISBN 13: 9783527290932
• Reliure: Broché
• Nombre de pages: 524
• Éditeur: Coppola Gary M., Schuster Herbert F.
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible