Description du livre Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. with contributions by numerous expertswith contributions by numerous experts|Includes supplementary material: sn.pub/extrasLess than 20 years ago the ?eld of cannabis and the cannabinoids was still c- sidered a minor, somewhat quaint, area of. N� de r�f. du vendeur 4885602

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Cannabinoids (Handbook of Experimental Pharmacology, 168)

Edit� par Springer (2005)

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Description du livre Hardcover. Etat : new. New. Fast Shipping and good customer service. N� de r�f. du vendeur Holz_New_354022565X

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Cannabinoids

Roger G. Pertwee

Edit� par Springer Berlin Heidelberg Mrz 2005 (2005)

ISBN 10 : 354022565X ISBN 13 : 9783540225652

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Description du livre Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Less than 20 years ago the eld of cannabis and the cannabinoids was still c- sidered a minor, somewhat quaint, area of research. A few groups were active in the eld, but it was already being viewed as stagnating. The chemistry of cannabis 9 9 was well known, -tetrahydrocannabinol ( -THC), identi ed in 1964, being the only major psychoactive constituent and cannabidiol, which is not psychoactive, possibly contributing to some of the effects. These cannabinoids and several s- thetic analogs had been thoroughly investigated for their pharmacological effects. Their mode of action was considered to be non-speci c. The reasons for this - sumption were both technical and conceptual. On the technical side, it had been shown that THC was active in both enantiomeric forms (though with a different level of potency) and this observation was incompatible with action on biological substrates-a receptor, an enzyme, an ion channel-which react with a single stereoisomer only. The conceptual problem related to THC activity. This had been pointed out by several highly regarded research groups that had shown that many of the effects seen with cannabinoids were related to those of biologically active lipophiles, and that many of the effects of THC, particularly chronic ones, were comparable to those seen with anaesthetics and solvents. 784 pp. Englisch. N� de r�f. du vendeur 9783540225652

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Cannabinoids

Roger G. Pertwee

Edit� par Springer Berlin Heidelberg (2005)

ISBN 10 : 354022565X ISBN 13 : 9783540225652

Neuf Couverture rigide Quantit� disponible : 1

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Description du livre Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Less than 20 years ago the eld of cannabis and the cannabinoids was still c- sidered a minor, somewhat quaint, area of research. A few groups were active in the eld, but it was already being viewed as stagnating. The chemistry of cannabis 9 9 was well known, -tetrahydrocannabinol ( -THC), identi ed in 1964, being the only major psychoactive constituent and cannabidiol, which is not psychoactive, possibly contributing to some of the effects. These cannabinoids and several s- thetic analogs had been thoroughly investigated for their pharmacological effects. Their mode of action was considered to be non-speci c. The reasons for this - sumption were both technical and conceptual. On the technical side, it had been shown that THC was active in both enantiomeric forms (though with a different level of potency) and this observation was incompatible with action on biological substrates-a receptor, an enzyme, an ion channel-which react with a single stereoisomer only. The conceptual problem related to THC activity. This had been pointed out by several highly regarded research groups that had shown that many of the effects seen with cannabinoids were related to those of biologically active lipophiles, and that many of the effects of THC, particularly chronic ones, were comparable to those seen with anaesthetics and solvents. N� de r�f. du vendeur 9783540225652

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