Synopsis
Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the "big picture" and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc, N-myc, L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli?cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
Autres éditions populaires du même titre
Résultats de recherche pour The Myc/Max/mad Transcription Factor Network
Image fournie par le vendeur
The Myc/Max/Mad Transcription Factor Network: 302 (Current Topics in Microbiology and Immunology, 302)
Edité par
Springer, 2006
ISBN 10 : 3540239685
ISBN 13 : 9783540239680
Ancien ou d'occasion
Couverture rigide
Vendeur : WeBuyBooks, Rossendale, LANCS, Royaume-Uni
Évaluation du vendeur 5 sur 5 étoiles
Etat : Like New. Most items will be dispatched the same or the next working day. An apparently unread copy in perfect condition. Dust cover is intact with no nicks or tears. Spine has no signs of creasing. Pages are clean and not marred by notes or folds of any kind. N° de réf. du vendeur wbs1932588208
Acheter D'occasion
EUR 52,39
Frais de port :
EUR 7,50
De Royaume-Uni vers Etats-Unis
Quantité disponible : 1 disponible(s)
Image d'archives
The Myc/max/mad Transcription Factor Network
Vendeur : Romtrade Corp., STERLING HEIGHTS, MI, Etats-Unis
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide. N° de réf. du vendeur ABNR-275267
Acheter neuf
EUR 101,03
Frais de port :
Gratuit
Vers Etats-Unis
Quantité disponible : 1 disponible(s)
Image d'archives
The Myc/max/mad Transcription Factor Network
Vendeur : Basi6 International, Irving, TX, Etats-Unis
Évaluation du vendeur 5 sur 5 étoiles
Etat : Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. N° de réf. du vendeur ABEOCT25-239411
Acheter neuf
EUR 101,03
Frais de port :
Gratuit
Vers Etats-Unis
Quantité disponible : 1 disponible(s)
Image d'archives
The Myc/Max/Mad Transcription Factor Network (Current Topics in Microbiology and Immunology, 302)
Vendeur : ALLBOOKS1, Direk, SA, Australie
Évaluation du vendeur 5 sur 5 étoiles
Brand new book. Fast ship. Please provide full street address as we are not able to ship to P O box address. N° de réf. du vendeur SHAK239411
Acheter neuf
EUR 110,53
Frais de port :
Gratuit
De Australie vers Etats-Unis
Quantité disponible : 1 disponible(s)
Image d'archives
The Myc/Max/Mad Transcription Factor Network
Vendeur : Books Puddle, New York, NY, Etats-Unis
Évaluation du vendeur 4 sur 5 étoiles
Etat : New. pp. xii + 284 1st Edition. N° de réf. du vendeur 26293239
Acheter neuf
EUR 107,62
Frais de port :
EUR 3,44
Vers Etats-Unis
Quantité disponible : 1 disponible(s)
Image d'archives
The Myc/Max/Mad Transcription Factor Network
Vendeur : Majestic Books, Hounslow, Royaume-Uni
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. pp. xii + 284. N° de réf. du vendeur 7587496
Acheter neuf
EUR 111,28
Frais de port :
EUR 7,37
De Royaume-Uni vers Etats-Unis
Quantité disponible : 1 disponible(s)
Image d'archives
The Myc/Max/Mad Transcription Factor Network
Vendeur : Biblios, Frankfurt am main, HESSE, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. pp. xii + 284. N° de réf. du vendeur 18293245
Acheter neuf
EUR 113,13
Frais de port :
EUR 9,95
De Allemagne vers Etats-Unis
Quantité disponible : 1 disponible(s)
Image d'archives
The Myc/Max/Mad Transcription Factor Network (Current Topics in Microbiology and Immunology, 302)
Vendeur : Lucky's Textbooks, Dallas, TX, Etats-Unis
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. N° de réf. du vendeur ABLIING23Mar3113020163801
Acheter neuf
EUR 158,58
Frais de port :
EUR 3,44
Vers Etats-Unis
Quantité disponible : Plus de 20 disponibles
Image d'archives
The Myc/Max/Mad Transcription Factor Network (Current Topics in Microbiology and Immunology, 302)
Vendeur : Ria Christie Collections, Uxbridge, Royaume-Uni
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. In. N° de réf. du vendeur ria9783540239680_new
Acheter neuf
EUR 156,68
Frais de port :
EUR 13,59
De Royaume-Uni vers Etats-Unis
Quantité disponible : Plus de 20 disponibles
Image fournie par le vendeur
The Myc/Max/Mad Transcription Factor Network
Edité par
Springer Berlin Heidelberg Feb 2006, 2006
ISBN 10 : 3540239685
ISBN 13 : 9783540239680
Neuf
Couverture rigide
Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the 'big picture' and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms. 300 pp. Englisch. N° de réf. du vendeur 9783540239680
Acheter neuf
EUR 160,49
Frais de port :
EUR 23
De Allemagne vers Etats-Unis
Quantité disponible : 2 disponible(s)