Description du livre Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Research in the eld of gene regulation is evolving rapidly in an ever-changing s- enti c environment. Microarray techniques and comparative genomics have enabled more comprehensive studies of regulatory genomics and are proving to be powerful tools of discovery. The application of chromatin immunoprecipitation and microarrays (chIP-on-chip) to directly study the genomic binding locations of transcription factors has enabled more comprehensive modeling of regulatory networks. In addition, c- plete genome sequences and the comparison of numerous related species has dem- strated that conservation in non-coding DNA sequences often provides evidence for cis-regulatory binding sites. That said, much is still to be learned about the regulatory networks of these sequenced genomes. Systematic methods to decipher the regulatory mechanism are also crucial for c- roboratingthese regulatorynetworks.Thecoreof thesemethodsarethe motifdiscovery algorithms that can help predict cis-regulatory elements. These DNA-motif discovery programsarebecomingmoresophisticatedandare beginningto leverageevidencefrom comparative genomics (phylogenetic footprinting) and chIP-on-chip studies. How to use these new sources of evidence is an active area of research. 126 pp. Englisch. N� de r�f. du vendeur 9783540244561

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Regulatory Genomics

. Ed(s): Eskin, Eleazar; Workman, C.

Edit� par Springer-Verlag Berlin and Heidelberg GmbH & Co. KG (2005)

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Description du livre Etat : New. Editor(s): Eskin, Eleazar; Workman, C. Series: Lecture Notes in Computer Science / Lecture Notes in Bioinformatics. Num Pages: 124 pages, biography. BIC Classification: PSAK1. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 6. Weight in Grams: 420. . 2005. Paperback. . . . . N� de r�f. du vendeur V9783540244561

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Regulatory Genomics : Recomb 2004 International Workshop, Rrg 2004, San Diego, Ca, Usa, March 26-27, 2004, Revised Selected Papers

Eskin, Eleazar (EDT); Workman, Chris (EDT)

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ISBN 10 : 3540244565 ISBN 13 : 9783540244561

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Description du livre Etat : New. N� de r�f. du vendeur 5906881-n

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Regulatory Genomics : RECOMB 2004 International Workshop, RRG 2004, San Diego, CA, USA, March 26-27, 2004, Revised Selected Papers

Chris Workman

Edit� par Springer Berlin Heidelberg (2005)

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Description du livre Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Research in the eld of gene regulation is evolving rapidly in an ever-changing s- enti c environment. Microarray techniques and comparative genomics have enabled more comprehensive studies of regulatory genomics and are proving to be powerful tools of discovery. The application of chromatin immunoprecipitation and microarrays (chIP-on-chip) to directly study the genomic binding locations of transcription factors has enabled more comprehensive modeling of regulatory networks. In addition, c- plete genome sequences and the comparison of numerous related species has dem- strated that conservation in non-coding DNA sequences often provides evidence for cis-regulatory binding sites. That said, much is still to be learned about the regulatory networks of these sequenced genomes. Systematic methods to decipher the regulatory mechanism are also crucial for c- roboratingthese regulatorynetworks.Thecoreof thesemethodsarethe motifdiscovery algorithms that can help predict cis-regulatory elements. These DNA-motif discovery programsarebecomingmoresophisticatedandare beginningto leverageevidencefrom comparative genomics (phylogenetic footprinting) and chIP-on-chip studies. How to use these new sources of evidence is an active area of research. N� de r�f. du vendeur 9783540244561

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