Hydrogel For Oral Mucositis: Formulation and in-vivo characterization of hydrogel for treatment of Chemo-radiotherapy induced oral mucositis - Couverture souple

Jain, Praveen Kumar; Kori, M. L.

 
9783639514056: Hydrogel For Oral Mucositis: Formulation and in-vivo characterization of hydrogel for treatment of Chemo-radiotherapy induced oral mucositis
Couverture souple
ISBN 10 : 363951405X ISBN 13 : 9783639514056
Editeur : Scholars' Press, 2013

Synopsis

As mucositis represents a significant clinical, and importantly, economic burden in oncology and stem cell or bone marrow transplantation. The aim of this study is to develop mucoadhesive system that can deliver the drug in the buccal cavity in effective concentration for prophylaxis and or treatment of oral mucositis. For this purpose hydrogel of L-glutamine with different polymer is prepared. It is crucial that the carrier gel matrix preserve physical and mechanical integrity. Mechanical stability of the gel is, therefore, a significant consideration when scheming a therapeutic system. The main benefit of hydrogel formulation is that it hold dose, which is adequate for therapeutic effect as it is positioned directly on the site of mucositis. Moreover this hydrogel is very tolerable and comfy because it is non-irritant and may be chosen over other adhesive dosage form in terms of flexibility, capability and protective to wounded or inflamed surfaces.

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Présentation de l'éditeur

As mucositis represents a significant clinical, and importantly, economic burden in oncology and stem cell or bone marrow transplantation. The aim of this study is to develop mucoadhesive system that can deliver the drug in the buccal cavity in effective concentration for prophylaxis and or treatment of oral mucositis. For this purpose hydrogel of L-glutamine with different polymer is prepared. It is crucial that the carrier gel matrix preserve physical and mechanical integrity. Mechanical stability of the gel is, therefore, a significant consideration when scheming a therapeutic system. The main benefit of hydrogel formulation is that it hold dose, which is adequate for therapeutic effect as it is positioned directly on the site of mucositis. Moreover this hydrogel is very tolerable and comfy because it is non-irritant and may be chosen over other adhesive dosage form in terms of flexibility, capability and protective to wounded or inflamed surfaces.

Biographie de l'auteur

Praveen Kumar Jain is an Assistant Professor in Pharmaceutical Sciences (Pharmaceutics). Mr. Jain has vast experience in industry and academic in various positions. Presently pursuing PhD. His area of interest include F&D,clinical research,New Drug Delivery system, DRA, nanotechnology

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Scholars' Press
Date d'édition
2013
Langue
anglais
ISBN 10 
363951405X
ISBN 13 
9783639514056
Reliure
Broché
Nombre de pages
140
Coordonnées du fabricant
non disponible
Personne responsable
non disponible