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The Role of Model Integration in Complex Systems Modelling: An Example from Cancer Biology - Couverture rigide
Synopsis
Model integration - the process by which different modelling efforts can be brought together to simulate the target system - is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that model integration poses, namely that of paradigm (the formalism on which a model is based), focus (the real-world system the model represents) and scale.
A two-tier model integration strategy, including a knowledge-driven approach to address model semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distilling a set of abstract classes and properties. These can accurately describe model behaviour and hence describe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour is decomposed into an agent-based system by translating the models into local interaction rules.
The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects, which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is self-supporting. It also includes an in-depth current bibliography to relevant research papers and literature. The review of the current state of the art in tumour modelling provides added value.
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The Role of Model Integration in Complex Systems Modelling : An Example from Cancer Biology
Edité par
Springer Berlin Heidelberg, 2010
ISBN 10 : 3642156029
ISBN 13 : 9783642156021
Ancien ou d'occasion
Couverture rigide
Vendeur : Buchpark, Trebbin, Allemagne
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Etat : Sehr gut. Zustand: Sehr gut | Seiten: 180 | Sprache: Englisch | Produktart: Bücher. N° de réf. du vendeur 8647912/12
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ROLE OF MODEL INTEGRATION IN COMPLEX SYSTEMS MODELLING: AN EXAMPLE FROM CANCER BIOLOGY, 1ST EDITION
Vendeur : Basi6 International, Irving, TX, Etats-Unis
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Etat : Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. N° de réf. du vendeur ABEJUNE24-272250
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The Role of Model Integration in Complex Systems Modelling
Edité par
Springer Berlin Heidelberg, 2010
ISBN 10 : 3642156029
ISBN 13 : 9783642156021
Neuf
Couverture rigide
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Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. First book on Complex Systems Science And Systems Biology of Cancer with outstanding importance for systems biology and tumour modelingContains advanced mathematical and computation principles applied to complex systems theory using tumours as an exampleInc. N° de réf. du vendeur 5050877
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The Role of Model Integration in Complex Systems Modelling: An Example from Cancer Biology
Edité par
Springer, Berlin, 2010
ISBN 10 : 3642156029
ISBN 13 : 9783642156021
Ancien ou d'occasion
Couverture rigide
Edition originale
Vendeur : Pride and Prejudice-Books, Ballston Lake, NY, Etats-Unis
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Hardcover. Etat : As New. 1st Edition. First Edition. Original Boards. As New. No Dust Jacket. N° de réf. du vendeur 020902
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The Role of Model Integration in Complex Systems Modelling : An Example from Cancer Biology
Edité par
Springer Berlin Heidelberg, 2010
ISBN 10 : 3642156029
ISBN 13 : 9783642156021
Neuf
Couverture rigide
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Model integration - the process by which different modelling efforts can be brought together to simulate the target system - is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that model integration poses, namely that of paradigm (the formalism on which a model is based), focus (the real-world system the model represents) and scale.A two-tier model integration strategy, including a knowledge-driven approach to address model semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distilling a set of abstract classes and properties. These can accurately describe model behaviour and hence describe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour is decomposed into an agent-based system by translating the models into local interaction rules.The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects, which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is self-supporting. It also includes an in-depth current bibliography to relevant research papers and literature. The review of the current state of the art in tumour modelling provides added value. N° de réf. du vendeur 9783642156021
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The Role of Model Integration in Complex Systems Modelling
Edité par
Springer Berlin Heidelberg Sep 2010, 2010
ISBN 10 : 3642156029
ISBN 13 : 9783642156021
Neuf
Couverture rigide
Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Model integration - the process by which different modelling efforts can be brought together to simulate the target system - is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that model integration poses, namely that of paradigm (the formalism on which a model is based), focus (the real-world system the model represents) and scale.A two-tier model integration strategy, including a knowledge-driven approach to address model semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distilling a set of abstract classes and properties. These can accurately describe model behaviour and hence describe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour is decomposed into an agent-based system by translating the models into local interaction rules.The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects, which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is self-supporting. It also includes an in-depth current bibliography to relevant research papers and literature. The review of the current state of the art in tumour modelling provides added value. 180 pp. Englisch. N° de réf. du vendeur 9783642156021
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The Role of Model Integration in Complex Systems Modelling: An Example from Cancer Biology (Understanding Complex Systems)
Vendeur : Ria Christie Collections, Uxbridge, Royaume-Uni
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The Role of Model Integration in Complex Systems Modelling
Edité par
Springer Berlin Heidelberg, Springer Berlin Heidelberg Sep 2010, 2010
ISBN 10 : 3642156029
ISBN 13 : 9783642156021
Neuf
Couverture rigide
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Buch. Etat : Neu. Neuware -Model integration ¿ the process by which different modelling efforts can be brought together to simulate the target system ¿ is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that model integration poses, namely that of paradigm (the formalism on which a model is based), focus (the real-world system the model represents) and scale.A two-tier model integration strategy, including a knowledge-driven approach to address model semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distilling a set of abstract classes and properties. These can accurately describe model behaviour and hence describe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour is decomposed into an agent-based system by translating the models into local interaction rules.The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects, which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is self-supporting. It also includes an in-depth current bibliography to relevant research papers and literature. The review of the current state of the art in tumour modelling provides added value.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 180 pp. Englisch. N° de réf. du vendeur 9783642156021
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The Role of Model Integration in Complex Systems Modelling: An Example from Cancer Biology (Understanding Complex Systems)
Vendeur : California Books, Miami, FL, Etats-Unis
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The Role of Model Integration in Complex Systems Modelling: An Example from Cancer Biology
Vendeur : Revaluation Books, Exeter, Royaume-Uni
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Hardcover. Etat : Brand New. 176 pages. 9.50x6.00x0.75 inches. In Stock. N° de réf. du vendeur x-3642156029
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