Description du livre Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Discovery of the mechanism for V(D)J hypermutation remains a basic goal of immunology despite the best efforts of many labo ratories. The existence of catalyzed, site-specific mutation and its exploitation for the somatic evolution of lymphocytes are re markable adaptations, yet since the discovery of hypermutation in 1970 (see cover), much hard work has generated little. Indeed, our knowledge of what is probably absolutely required for the mutator's action can be succinctly expressed: /g gene enhancers. Table 1 of Winter et a!.'s chapter puts into a historical perspec tive how our notions of the mutator have changed over the years. Despite these modest gains, most of us feel that this is the best of times. Our work has not only shown us what the mutator is not, it has also, like an artist's preliminary sketch, defined the questions and experiments we must face without diminishing the potential for new biology. In short, it is great fun to toil against a significant and enigmatic problem. 240 pp. Englisch. N� de r�f. du vendeur 9783642719868

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Somatic Diversification of Immune Responses

Kelsoe, Garnett (EDT); Flajnik, Martin (EDT)

Edit� par Springer (2011)

ISBN 10 : 3642719864 ISBN 13 : 9783642719868

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Description du livre Etat : New. N� de r�f. du vendeur 18758267-n

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Somatic Diversification of Immune Responses

Kelsoe, Garnett|Flajnik, Martin

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ISBN 10 : 3642719864 ISBN 13 : 9783642719868

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Description du livre Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. As knowledge from experimentation accumulates, we begin to have a somewhat clearer picture of the muation/conversion process(es). This volume takes one step forward in the analysis of somatic diversification.Discovery of the mechanism for V(D)J hypermut. N� de r�f. du vendeur 5068929

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Somatic Diversification of Immune Responses

Martin Flajnik

Edit� par Springer Berlin Heidelberg (2011)

ISBN 10 : 3642719864 ISBN 13 : 9783642719868

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Description du livre Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Discovery of the mechanism for V(D)J hypermutation remains a basic goal of immunology despite the best efforts of many labo ratories. The existence of catalyzed, site-specific mutation and its exploitation for the somatic evolution of lymphocytes are re markable adaptations, yet since the discovery of hypermutation in 1970 (see cover), much hard work has generated little. Indeed, our knowledge of what is probably absolutely required for the mutator's action can be succinctly expressed: /g gene enhancers. Table 1 of Winter et a!.'s chapter puts into a historical perspec tive how our notions of the mutator have changed over the years. Despite these modest gains, most of us feel that this is the best of times. Our work has not only shown us what the mutator is not, it has also, like an artist's preliminary sketch, defined the questions and experiments we must face without diminishing the potential for new biology. In short, it is great fun to toil against a significant and enigmatic problem. N� de r�f. du vendeur 9783642719868

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Somatic Diversification of Immune Responses (Current Topics in Microbiology and Immunology)

Kelsoe, Garnett (Editor) / Flajnik, Martin (Editor)

Edit� par Springer-Verlag (2012)

ISBN 10 : 3642719864 ISBN 13 : 9783642719868

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Description du livre Paperback. Etat : Brand New. reprint edition. 231 pages. 9.25x6.10x0.50 inches. In Stock. N� de r�f. du vendeur x-3642719864

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Somatic Diversification of Immune Responses

. Ed(s): Kelsoe, Garnett; Flajnik, Martin

Edit� par Springer-Verlag Berlin and Heidelberg GmbH & Co. KG (2011)

ISBN 10 : 3642719864 ISBN 13 : 9783642719868

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Description du livre Etat : New. Editor(s): Kelsoe, Garnett; Flajnik, Martin. Series: Current Topics in Microbiology and Immunology. Num Pages: 231 pages, 23 black & white tables, biography. BIC Classification: MBGR; MJCM; PSF; PSG; PSVD. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 12. Weight in Grams: 370. . 2011. Softcover reprint of the original 1st ed. 1998. Paperback. . . . . N� de r�f. du vendeur V9783642719868

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