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Drug - Drug Interaction Studies of Prazosin: Prazosin interacts with drugs like ACE- inhibitors, calcium channel blockers, H2 receptor antagonists, NSAID’s, statins - Couverture souple
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In this work, we investigated the “in vitro” interactions of prazosin with frequently prescribed and co-administered drugs in simulated human body environments and thus to infer about the combination therapy. The interacting drugs selected for interaction with prazosin are ACE-inhibitors (captopril, enalapril and lisinopril), calcium channel blockers (amlodipine, diltiazem and verapamil), H2 receptor antagonists (cimetidine, famotidine and ranitidine), NSAID’s (diclofenac sodium, flurbiprofen, mefenamic acid, meloxicam and naproxen), statins (atorvastatin, rosuvastatin and simvastatin) and hydrated salts of essential and trace elements (magnesium, calcium, chromium, manganese, ferric, cobalt, nickel, copper, zinc and cadmium). These interactions were conducted in simulated gastric juice (pH 1), simulating full stomach (pH 4), simulating blood pH (pH 7.4) and simulating intestinal pH (pH 9) using UV/visible spectrophotometric and reversed phase high performance liquid chromatography (RP-HPLC).Prior to start the drug interaction studies, assay methods for the simultaneous quantitation of prazosin and interacting drugs were developed using UV/UV/visible spectrophotometer and RP-HPLC.
Biographie de l'auteur :
Dr. Shabana Naz Shah has obtained her PhD. Degree in Pharmaceutical Chemistry in October 2011 from University of Karachi. She has worked in Pfizer Pakistan Limited as an Assist. Manager of Training, Validation and Stability. She joined Parke-Davis & Co. ltd. in 1999. She is the author of several articles published in reputed journals.
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- ÉditeurLAP Lambert Academic Publishing
- Date d'édition2012
- ISBN 10 3659125199
- ISBN 13 9783659125195
- ReliureBroché
- Nombre de pages272
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Drug - Drug Interaction Studies of Prazosin: Prazosin interacts with drugs like ACE- inhibitors, calcium channel blockers, H2 receptor antagonists, NSAID's, statins
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LAP LAMBERT Academic Publishing
(2012)
ISBN 10 : 3659125199
ISBN 13 : 9783659125195
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Drug - Drug Interaction Studies of Prazosin
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LAP Lambert Academic Publishing
(2012)
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ISBN 13 : 9783659125195
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Description du livre Etat : New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. N° de réf. du vendeur ria9783659125195_lsuk
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Drug - Drug Interaction Studies of Prazosin
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Drug - Drug Interaction Studies of Prazosin
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Description du livre Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this work, we investigated the 'in vitro' interactions of prazosin with frequently prescribed and co-administered drugs in simulated human body environments and thus to infer about the combination therapy. The interacting drugs selected for interaction with prazosin are ACE-inhibitors (captopril, enalapril and lisinopril), calcium channel blockers (amlodipine, diltiazem and verapamil), H2 receptor antagonists (cimetidine, famotidine and ranitidine), NSAID's (diclofenac sodium, flurbiprofen, mefenamic acid, meloxicam and naproxen), statins (atorvastatin, rosuvastatin and simvastatin) and hydrated salts of essential and trace elements (magnesium, calcium, chromium, manganese, ferric, cobalt, nickel, copper, zinc and cadmium). These interactions were conducted in simulated gastric juice (pH 1), simulating full stomach (pH 4), simulating blood pH (pH 7.4) and simulating intestinal pH (pH 9) using UV/visible spectrophotometric and reversed phase high performance liquid chromatography (RP-HPLC).Prior to start the drug interaction studies, assay methods for the simultaneous quantitation of prazosin and interacting drugs were developed using UV/UV/visible spectrophotometer and RP-HPLC. 272 pp. Englisch. N° de réf. du vendeur 9783659125195
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Drug Drug Interaction Studies of Prazosin Prazosin interacts with drugs like ACE inhibitors, calcium channel blockers, H2 receptor antagonists, NSAIDs, statins
Edité par
LAP LAMBERT Academic Publishing
(2012)
ISBN 10 : 3659125199
ISBN 13 : 9783659125195
Neuf
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Description du livre PAP. Etat : New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. N° de réf. du vendeur L0-9783659125195
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Drug - Drug Interaction Studies of Prazosin : Prazosin interacts with drugs like ACE- inhibitors, calcium channel blockers, H2 receptor antagonists, NSAID¿s, statins
Edité par
LAP LAMBERT Academic Publishing
(2012)
ISBN 10 : 3659125199
ISBN 13 : 9783659125195
Neuf
Taschenbuch
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Description du livre Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - In this work, we investigated the 'in vitro' interactions of prazosin with frequently prescribed and co-administered drugs in simulated human body environments and thus to infer about the combination therapy. The interacting drugs selected for interaction with prazosin are ACE-inhibitors (captopril, enalapril and lisinopril), calcium channel blockers (amlodipine, diltiazem and verapamil), H2 receptor antagonists (cimetidine, famotidine and ranitidine), NSAID's (diclofenac sodium, flurbiprofen, mefenamic acid, meloxicam and naproxen), statins (atorvastatin, rosuvastatin and simvastatin) and hydrated salts of essential and trace elements (magnesium, calcium, chromium, manganese, ferric, cobalt, nickel, copper, zinc and cadmium). These interactions were conducted in simulated gastric juice (pH 1), simulating full stomach (pH 4), simulating blood pH (pH 7.4) and simulating intestinal pH (pH 9) using UV/visible spectrophotometric and reversed phase high performance liquid chromatography (RP-HPLC).Prior to start the drug interaction studies, assay methods for the simultaneous quantitation of prazosin and interacting drugs were developed using UV/UV/visible spectrophotometer and RP-HPLC. N° de réf. du vendeur 9783659125195
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EUR 79
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Drug - Drug Interaction Studies of Prazosin
Edité par
LAP LAMBERT Academic Publishing
(2012)
ISBN 10 : 3659125199
ISBN 13 : 9783659125195
Neuf
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Description du livre Kartoniert / Broschiert. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Naz Shah ShabanaDr. Shabana Naz Shah has obtained her PhD. Degree in Pharmaceutical Chemistry in October 2011 from University of Karachi. She has worked in Pfizer Pakistan Limited as an Assist. Manager of Training, Validation and Sta. N° de réf. du vendeur 5133175
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Drug Drug Interaction Studies of Prazosin Prazosin interacts with drugs like ACE inhibitors, calcium channel blockers, H2 receptor antagonists, NSAIDs, statins
Edité par
LAP LAMBERT Academic Publishing
(2012)
ISBN 10 : 3659125199
ISBN 13 : 9783659125195
Neuf
PAP
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Description du livre PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. N° de réf. du vendeur L0-9783659125195
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