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Buccal Systems to Enhance Buspirone Hydrochloride Bioavailability: Formulation and In-vitro / In-vivo Evaluation - Couverture souple
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Buccal delivery systems involves the administration of the drug through the buccal mucosal membrane lining of the oral cavity bypassing the first pass effect. Buspirone hydrochloride is an anxiolytic drug which undergoes extensive first-pass metabolism that results in very low oral bioavailability (4%). In addition, buspirone hydrochloride has short and variable elimination half–life (approximately 2.4 h). So it is a good candidate for the preparation of sustained release buccal dosage forms. The aim of this work was to formulate and evaluate buspirone hydrochloride buccal mucoadhesive cup and core tablets and sponges to sustain its action and improve its systemic bioavailability. The results of the in-vivo performance study confirmed that the prepared cup and core buccal tablets succeeded in increasing the bioavailability of buspirone 5.6 folds in comparison to the oral immediate release market product.
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- ÉditeurLAP Lambert Academic Publishing
- Date d'édition2014
- ISBN 10 3659665932
- ISBN 13 9783659665936
- ReliureBroché
- Nombre de pages328
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Buccal Systems to Enhance Buspirone Hydrochloride Bioavailability: Formulation and In-vitro / In-vivo Evaluation
Edité par
LAP LAMBERT Academic Publishing
(2014)
ISBN 10 : 3659665932
ISBN 13 : 9783659665936
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Couverture souple
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Description du livre Etat : New. N° de réf. du vendeur ABLIING23Mar3113020299224
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Buccal Systems to Enhance Buspirone Hydrochloride Bioavailability Formulation and Invitro Invivo Evaluation
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LAP LAMBERT Academic Publishing
(2014)
ISBN 10 : 3659665932
ISBN 13 : 9783659665936
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Description du livre PAP. Etat : New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. N° de réf. du vendeur L0-9783659665936
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Buccal Systems to Enhance Buspirone Hydrochloride Bioavailability
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LAP LAMBERT Academic Publishing Dez 2014
(2014)
ISBN 10 : 3659665932
ISBN 13 : 9783659665936
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Description du livre Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Buccal delivery systems involves the administration of the drug through the buccal mucosal membrane lining of the oral cavity bypassing the first pass effect. Buspirone hydrochloride is an anxiolytic drug which undergoes extensive first-pass metabolism that results in very low oral bioavailability (4%). In addition, buspirone hydrochloride has short and variable elimination half-life (approximately 2.4 h). So it is a good candidate for the preparation of sustained release buccal dosage forms. The aim of this work was to formulate and evaluate buspirone hydrochloride buccal mucoadhesive cup and core tablets and sponges to sustain its action and improve its systemic bioavailability. The results of the in-vivo performance study confirmed that the prepared cup and core buccal tablets succeeded in increasing the bioavailability of buspirone 5.6 folds in comparison to the oral immediate release market product. 328 pp. Englisch. N° de réf. du vendeur 9783659665936
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Buccal Systems to Enhance Buspirone Hydrochloride Bioavailability
Edité par
LAP Lambert Academic Publishing
(2014)
ISBN 10 : 3659665932
ISBN 13 : 9783659665936
Neuf
Couverture souple
Quantité disponible : > 20
Vendeur :
Evaluation vendeur
Description du livre Etat : New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. N° de réf. du vendeur ria9783659665936_lsuk
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Buccal Systems to Enhance Buspirone Hydrochloride Bioavailability
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LAP Lambert Academic Publishing 2014-12
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ISBN 13 : 9783659665936
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Description du livre PF. Etat : New. N° de réf. du vendeur 6666-IUK-9783659665936
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Buccal Systems to Enhance Buspirone Hydrochloride Bioavailability
Edité par
LAP LAMBERT Academic Publishing
(2014)
ISBN 10 : 3659665932
ISBN 13 : 9783659665936
Neuf
Couverture souple
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Evaluation vendeur
Description du livre Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Roshdy Fares AhmedAhmed Roshdy Fares, MSc. Teaching and research assistant in Pharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy - Cairo university. Earned a Master degree in Pharmaceutical Sciences.Buccal deli. N° de réf. du vendeur 5171312
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Buccal Systems to Enhance Buspirone Hydrochloride Bioavailability : Formulation and In-vitro / In-vivo Evaluation
Edité par
LAP LAMBERT Academic Publishing
(2014)
ISBN 10 : 3659665932
ISBN 13 : 9783659665936
Neuf
Taschenbuch
Quantité disponible : 1
Vendeur :
Evaluation vendeur
Description du livre Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Buccal delivery systems involves the administration of the drug through the buccal mucosal membrane lining of the oral cavity bypassing the first pass effect. Buspirone hydrochloride is an anxiolytic drug which undergoes extensive first-pass metabolism that results in very low oral bioavailability (4%). In addition, buspirone hydrochloride has short and variable elimination half-life (approximately 2.4 h). So it is a good candidate for the preparation of sustained release buccal dosage forms. The aim of this work was to formulate and evaluate buspirone hydrochloride buccal mucoadhesive cup and core tablets and sponges to sustain its action and improve its systemic bioavailability. The results of the in-vivo performance study confirmed that the prepared cup and core buccal tablets succeeded in increasing the bioavailability of buspirone 5.6 folds in comparison to the oral immediate release market product. N° de réf. du vendeur 9783659665936
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EUR 87,90
Autre devise
Image d'archives
Buccal Systems to Enhance Buspirone Hydrochloride Bioavailability Formulation and Invitro Invivo Evaluation
Edité par
LAP LAMBERT Academic Publishing
(2014)
ISBN 10 : 3659665932
ISBN 13 : 9783659665936
Neuf
PAP
Quantité disponible : > 20
Vendeur :
Evaluation vendeur
Description du livre PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. N° de réf. du vendeur L0-9783659665936
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