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Medicinal properties of Bulbine natalensis: In Vitro Anti-platelet Aggregation Activity of the extracts of Bulbine natalensis - Couverture souple
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Présentation de l'éditeur :
Bulbine natalensis Baker is a medicinal plant with succulent, aloe-like leaves from the Asphodelaceae family, commonly used by traditional healers to treat blood clotting-related diseases. This research tested the anti-platelet aggregation effect of B.natalensis’ extracts on rat platelet aggregation separately induced by thrombin, ADP, collagen, epinephrine, papain, bromelain and trypsin. Fresh plant material was extracted sequentially using hexane, chloroform, ethyl acetate, methanol, and water. The chloroform extract had the highest yield. Phytochemical screening revealed the presence of anthraquinones, cardiac glycosides, saponins, tannins, flavonoids and alkaloids. The hexane extract revealed the highest contents of total phenols, flavonoids and proanthocyanidin. Hexane extract also displayed the highest ABTS scavenging activity. Studies reveal that B.natalensis is a good antioxidant. Anti-platelet aggregation activities on rat platelets were observed. The chloroform extract inhibited ADP-induced clotting by 100%. Two compounds were isolated but they were unstable. Based on the spectra obtained and comparing to existing literature data, they were envisaged to be a knipholone.
Biographie de l'auteur :
Geraldine Lazarus obtained her Masters in Biochemistry (2010) at the University of Zululand,(S.A.) She is an Abe Bailey 2010 and Erasmus Mundus 2012 scholar. Currently, she is a doctoral candidate researching the synthesis of gold nano-particles and its interactions with mammalian cells at the Dept. of Applied Physics, University of Granada, Spain.
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- ÉditeurLAP LAMBERT Academic Publishing
- Date d'édition2012
- ISBN 10 3848431769
- ISBN 13 9783848431762
- ReliureBroché
- Nombre de pages128
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Medicinal properties of Bulbine natalensis: In Vitro Anti-platelet Aggregation Activity of the extracts of Bulbine natalensis
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LAP LAMBERT Academic Publishing
(2012)
ISBN 10 : 3848431769
ISBN 13 : 9783848431762
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Medicinal properties of Bulbine natalensis In Vitro Antiplatelet Aggregation Activity of the extracts of Bulbine natalensis
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LAP LAMBERT Academic Publishing
(2012)
ISBN 10 : 3848431769
ISBN 13 : 9783848431762
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Medicinal properties of Bulbine natalensis: In Vitro Anti-platelet Aggregation Activity of the extracts of Bulbine natalensis
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Description du livre Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Bulbine natalensis Baker is a medicinal plant with succulent, aloe-like leaves from the Asphodelaceae family, commonly used by traditional healers to treat blood clotting-related diseases. This research tested the anti-platelet aggregation effect of B.natalensis' extracts on rat platelet aggregation separately induced by thrombin, ADP, collagen, epinephrine, papain, bromelain and trypsin. Fresh plant material was extracted sequentially using hexane, chloroform, ethyl acetate, methanol, and water. The chloroform extract had the highest yield. Phytochemical screening revealed the presence of anthraquinones, cardiac glycosides, saponins, tannins, flavonoids and alkaloids. The hexane extract revealed the highest contents of total phenols, flavonoids and proanthocyanidin. Hexane extract also displayed the highest ABTS scavenging activity. Studies reveal that B.natalensis is a good antioxidant. Anti-platelet aggregation activities on rat platelets were observed. The chloroform extract inhibited ADP-induced clotting by 100%. Two compounds were isolated but they were unstable. Based on the spectra obtained and comparing to existing literature data, they were envisaged to be a knipholone. 128 pp. Englisch. N° de réf. du vendeur 9783848431762
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Medicinal properties of Bulbine natalensis : In Vitro Anti-platelet Aggregation Activity of the extracts of Bulbine natalensis
Edité par
LAP Lambert Academic Publishing
(2012)
ISBN 10 : 3848431769
ISBN 13 : 9783848431762
Neuf
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Description du livre Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Bulbine natalensis Baker is a medicinal plant with succulent, aloe-like leaves from the Asphodelaceae family, commonly used by traditional healers to treat blood clotting-related diseases. This research tested the anti-platelet aggregation effect of B.natalensis' extracts on rat platelet aggregation separately induced by thrombin, ADP, collagen, epinephrine, papain, bromelain and trypsin. Fresh plant material was extracted sequentially using hexane, chloroform, ethyl acetate, methanol, and water. The chloroform extract had the highest yield. Phytochemical screening revealed the presence of anthraquinones, cardiac glycosides, saponins, tannins, flavonoids and alkaloids. The hexane extract revealed the highest contents of total phenols, flavonoids and proanthocyanidin. Hexane extract also displayed the highest ABTS scavenging activity. Studies reveal that B.natalensis is a good antioxidant. Anti-platelet aggregation activities on rat platelets were observed. The chloroform extract inhibited ADP-induced clotting by 100%. Two compounds were isolated but they were unstable. Based on the spectra obtained and comparing to existing literature data, they were envisaged to be a knipholone. N° de réf. du vendeur 9783848431762
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Medicinal properties of Bulbine natalensis In Vitro Antiplatelet Aggregation Activity of the extracts of Bulbine natalensis
Edité par
LAP LAMBERT Academic Publishing
(2012)
ISBN 10 : 3848431769
ISBN 13 : 9783848431762
Neuf
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Description du livre PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. N° de réf. du vendeur L0-9783848431762
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Medicinal properties of Bulbine natalensis
Edité par
LAP LAMBERT Academic Publishing
(2012)
ISBN 10 : 3848431769
ISBN 13 : 9783848431762
Neuf
Couverture souple
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Description du livre Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Lazarus Geraldine GeneviveGeraldine Lazarus obtained her Masters in Biochemistry (2010) at the University of Zululand,(S.A.) She is an Abe Bailey 2010 and Erasmus Mundus 2012 scholar. Currently, she is a doctoral candidate researchin. N° de réf. du vendeur 5521713
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