Odor Memory and Perception - Couverture rigide

Couverture rigide

ISBN 10 : 0444633502 ISBN 13 : 9780444633507

Editeur : Elsevier Science Ltd, 2014

A propos du livre

Biographie de l'auteur :

Edi Barkai, Ph.D. - I received my doctorate from Ben-Gurion University in Israel and post-doctoral training at the psychology department at Harvard. I am currently Professor of physiology and Dean of the Faculty of Natural Sciences at the University of Haifa, Israel. My primary interest is the cellular mechanisms underlying learning and memory in the mammalian brain. In particular, I have been studying the biological bases of higher-skill learning. To that aim, I adopted a complex olfactory-discrimination task. Training rats in this particularly difficult task results with acquisition of superb capabilities to perform complex tasks, termed ‘rule learning’ or ‘learning set. The long-term modifications at the cellular, sub cellular and network levels that enable 'rule learning' acquisition and maintenance have been the subject of our research. We have been focusing on several key questions; what are the physiological, morphological and molecular mechanisms that enable the induction and long-term maintenance of enhanced learning capabilities? What roles do different brain areas have in these enhanced capabilities? How is the balanced activity maintained in the relevant neuronal networks in face of such multiple changes? We showed that at the cellular level learning-induced long-term modifications occur in the three components controlling neurons activation; the excitatory synaptic, the intrinsic neuronal excitability, and synaptic inhibition. Such modifications are maintained by persistent activation of key second messenger systems. Based on our result, we have been also engaged in developing a cognitive enhancer that will compensate for aging-induced and neurodegeneration-induced decline in cognitive capabilities.

Présentation de l'éditeur :

This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume explores interdisciplinary research on invertebrate and vertebrate models of odor memory and perception, as well as human odor memory and perception. This book brings together a collection of authors that cut across model systems, techniques, levels of analysis and questions to highlight important and exciting advances in the area of olfactory memory and perception. The chapters highlight the unique aspects of olfactory system anatomy, local circuit function, odor coding and plasticity. The authors are leading authorities in the field.

• Written by the leading researchers in the field of olfactory perception and memory
• Includes diverse models systems from invertebrates to humans
• Includes diverse technical approaches to the study of olfactory memory and perception
• Includes overview of the most recent research advances in this field

À propos de cette édition

• Éditeur: Elsevier Science Ltd
• Date d'édition: 2014
• ISBN 10: 0444633502
• ISBN 13: 9780444633507
• Reliure: Relié
• Numéro d'édition: 1
• Nombre de pages: 370