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Edité par Morgan & Claypool Publishers, United States, San Rafael, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : WorldofBooks, Goring-By-Sea, WS, Royaume-Uni
Livre
Paperback. Etat : Very Good. Proprotein convertases (PCs) are a family of proteases including PC1, PC2, Furin, PC4, PACE4, PC5, and PC7. These enzymes are involved in the maturation of many precursor proteins involved in the process of tumorigenesis and metastasis. Since their discovery, PCs were suggested as potential targets for anti-cancer therapy, and their activity was found to directly affect tumor cell proliferation, migration invasion, and the malignant phenotypes of tumor cells. Here, we discuss a number of previous and recent findings on the PCs features, their implication in the regulation of multiple cellular functions that impact on the invasive/metastatic potential of cancer cells, and their clinical relevance in cancer patients. Among the substrates of the proprotein convertases, various growth factors, their receptors, adhesion molecules, and proteases were identified. The PCs are inhibited by endogenous and exogenous inhibitors. To date, only pro7B2, a specific chaperone of PC2, and the granine-like precursor of neuroendocrine protein proSAAS, a selective ligand of PC1, have been identified as endogenous inhibitors of the PCs found in the regulated pathway. However, only PCs prosegments, several bioengineered inhibitors, peptides, and non-peptide compounds were found to inhibit the activity of the PCs found in the secretory pathway. The book has been read, but is in excellent condition. Pages are intact and not marred by notes or highlighting. The spine remains undamaged.
Edité par Morgan & Claypool Life Sciences, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : suffolkbooks, Center moriches, NY, Etats-Unis
Livre
Etat : VeryGood. Fast Shipping - Safe and Secure 7 days a week!.
Edité par Springer, 2006
Vendeur : Antiquariat Thomas Haker GmbH & Co. KG, Berlin, Allemagne
Membre d'association : GIAQ
Livre
Hardcover/Pappeinband. 167 p. Very good. Shrink wrapped. / Sehr guter Zustand. In Folie verschweißt. Sprache: Englisch Gewicht in Gramm: 478.
Edité par Springer, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : Books Puddle, New York, NY, Etats-Unis
Livre
Etat : New. pp. 168.
Edité par Springer, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : Majestic Books, Hounslow, Royaume-Uni
Livre
Etat : New. pp. 168 52:B&W 6.14 x 9.21in or 234 x 156mm (Royal 8vo) Case Laminate on White w/Gloss Lam.
Edité par Morgan & Claypool Life Sciences, 2013
ISBN 10 : 1615046100ISBN 13 : 9781615046102
Vendeur : suffolkbooks, Center moriches, NY, Etats-Unis
Livre
Etat : LikeNew. Fast Shipping - Safe and Secure 7 days a week!.
Edité par SP SPRINGER, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : Universal Store, Princeton Junction, NJ, Etats-Unis
Livre
Etat : Brand New. Brand New! Fast Delivery , Delivery with in 6-9 working Day Only , Original Edition. Excellent Quality, Printing In English Language, Quick delivery by FEDEX & DHL. Our courier service is not available at PO BOX& APO BOX.
Edité par Springer, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : Basi6 International, Irving, TX, Etats-Unis
Livre
Etat : Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Edité par Springer, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : Romtrade Corp., STERLING HEIGHTS, MI, Etats-Unis
Livre
Etat : New. Brand New Original US Edition.We Ship to PO BOX Address also. EXPEDITED shipping option also available for faster delivery.This item may ship from the US or other locations in India depending on your location and availability.
Edité par Springer, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : SMASS Sellers, IRVING, TX, Etats-Unis
Livre
Etat : New. Brand New Original US Edition. Customer service! Satisfaction Guaranteed. This item may ship from the US or our Overseas warehouse depending on your location and stock availability. We Ship to PO BOX Location also.
Edité par Springer, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : Basi6 International, Irving, TX, Etats-Unis
Livre
Etat : Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Edité par Springer, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : Romtrade Corp., STERLING HEIGHTS, MI, Etats-Unis
Livre
Etat : New. Brand New Original US Edition.We Ship to PO BOX Address also. EXPEDITED shipping option also available for faster delivery.This item may ship from the US or other locations in India depending on your location and availability.
Edité par Springer, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : SMASS Sellers, IRVING, TX, Etats-Unis
Livre
Etat : New. Brand New Original US Edition. Customer service! Satisfaction Guaranteed. This item may ship from the US or our Overseas warehouse depending on your location and stock availability. We Ship to PO BOX Location also.
Edité par Morgan & Claypool Life Sciences, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : booksXpress, Bayonne, NJ, Etats-Unis
Livre
Soft Cover. Etat : new.
Edité par Morgan & Claypool Life Sciences, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : Lucky's Textbooks, Dallas, TX, Etats-Unis
Livre
Etat : New.
Edité par Morgan and Claypool Publishers, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : PBShop.store US, Wood Dale, IL, Etats-Unis
Livre impression à la demande
PAP. Etat : New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Edité par Biota Publishing, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : Ria Christie Collections, Uxbridge, Royaume-Uni
Livre impression à la demande
Etat : New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Edité par Morgan & Claypool Life Sciences, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : Revaluation Books, Exeter, Royaume-Uni
Livre
Paperback. Etat : Brand New. 84 pages. 9.25x7.50x0.19 inches. In Stock.
Edité par Biota Publishing 2013-02, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : Chiron Media, Wallingford, Royaume-Uni
Livre
PF. Etat : New.
Edité par Morgan & Claypool Life Sciences, 2013
ISBN 10 : 1615046100ISBN 13 : 9781615046102
Vendeur : Lucky's Textbooks, Dallas, TX, Etats-Unis
Livre
Etat : New.
Edité par Morgan & Claypool, 2013
ISBN 10 : 1615046100ISBN 13 : 9781615046102
Vendeur : booksXpress, Bayonne, NJ, Etats-Unis
Livre impression à la demande
Soft Cover. Etat : new. This item is printed on demand.
Edité par Morgan & Claypool Publishers, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : THE SAINT BOOKSTORE, Southport, Royaume-Uni
Livre impression à la demande
Paperback / softback. Etat : New. This item is printed on demand. New copy - Usually dispatched within 5-9 working days.
Edité par Springer, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : Basi6 International, Irving, TX, Etats-Unis
Livre
Etat : Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Edité par Springer, 2006
ISBN 10 : 1402047932ISBN 13 : 9781402047930
Vendeur : Basi6 International, Irving, TX, Etats-Unis
Livre
Etat : Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Edité par Morgan and Claypool Publishers, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : PBShop.store UK, Fairford, GLOS, Royaume-Uni
Livre impression à la demande
PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Edité par Biota Publishing, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
Livre impression à la demande
Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Proprotein convertases (PCs) are a family of proteases including PC1, PC2, Furin, PC4, PACE4, PC5, and PC7. These enzymes are involved in the maturation of many precursor proteins involved in the process of tumorigenesis and metastasis. Since their discovery, PCs were suggested as potential targets for anti-cancer therapy, and their activity was found to directly affect tumor cell proliferation, migration invasion, and the malignant phenotypes of tumor cells. Here, we discuss a number of previous and recent findings on the PCs features, their implication in the regulation of multiple cellular functions that impact on the invasive/metastatic potential of cancer cells, and their clinical relevance in cancer patients.Among the substrates of the proprotein convertases, various growth factors, their receptors, adhesion molecules, and proteases were identified. The PCs are inhibited by endogenous and exogenous inhibitors. To date, only pro7B2, a specific chaperone of PC2, and the granine-like precursor of neuroendocrine protein proSAAS, a selective ligand of PC1, have been identified as endogenous inhibitors of the PCs found in the regulated pathway. However, only PCs prosegments, several bioengineered inhibitors, peptides, and non-peptide compounds were found to inhibit the activity of the PCs found in the secretory pathway.
Edité par Biota Publishing, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : moluna, Greven, Allemagne
Livre impression à la demande
Kartoniert / Broschiert. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Proprotein convertases (PCs) are a family of proteases including PC1, PC2, Furin, PC4, PACE4, PC5, and PC7. This title discusses a number of previous and recent findings on the PCs features, their implication in the regulation of multiple cellular functions.
Edité par Morgan & Claypool Life Sciences, 2013
ISBN 10 : 1615045368ISBN 13 : 9781615045365
Vendeur : Mispah books, Redhill, SURRE, Royaume-Uni
Livre
Paperback. Etat : Like New. Like New. book.
Edité par Biota Publishing, 2013
ISBN 10 : 1615046100ISBN 13 : 9781615046102
Vendeur : moluna, Greven, Allemagne
Livre impression à la demande
Kartoniert / Broschiert. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides an overview of angiogenesis processes and discusses the importance of VEGF-C and VEGF-D precursors processing by the proprotein convertases during the activation of VEGFR-2 and VEGFR-3 receptors and the mediation of their functions during angiogene.
Edité par Morgan & Claypool Life Sciences, 2013
ISBN 10 : 1615046267ISBN 13 : 9781615046263
Vendeur : Revaluation Books, Exeter, Royaume-Uni
Livre
Paperback. Etat : Brand New. 9.25x7.50x0.20 inches. In Stock.