springer japan mrz 2012 (24 résultats)

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Malignant glioma is generally considered one of the most therapeutically difficult cerebral tumors. This book deals with many aspects of gliomas, including factors related to incidence and epidemiology, and surveys the history of glioma therapies. Experimental studies carried out by the Sendai Group of Neurosurgeons are reported, together with the results of many clinical studies of RAFP therapy. This particular theorapy involves the administration of radiation treatment and three chemical compounds: ACNU, Futraful and PSK. A recent technique for evaluating the effectiveness of therapy based on MRI diagnostic methods is introduced. This book thus offers valuable information and guidelines for future developments in treatment. 256 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aging of society is a growing concern in all advanced nations, and at the forefront of concern is long-term care for frail older people. Enactment of a new public long-term care insurance program by the Japanese government in 1997 provided an excellent opportunity for a conference focusing on an ideal long-term care system for frail older people. The conference was organized around four major themes: Social aspects, including family dynamics and the role of formal providers; Clinical aspects, including effective treatments for physical and mental disabilities; Macroeconomic and macropolitical settings for public policy; Program design and management issues. With contributions from the fields of medicine, nursing, social work, gerontology, political science, economics, and sociology, this volume provides an overview of key problems and possible solutions in programs for frail older people from a unique international perspective. 268 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents the proceedings of COMPUTER GRAPHICS INTERNATIONAL '93 (COl '93), the Eleventh International Conference of the Computer Graphics Society (CGS), COl '93 has been held in Lausanne, Switzerland from June 21-25,1993 under the theme Communicating with Virtual Worlds. Since its foundation in 1983, COl conference has continued to attract high qUality research articles in all aspects of computer graphics and its applications. Previous conferences in this series were held in Japan (1983-1987), in Switzerland (1988), in the United Kingdom (1989), in Singapore (1990), in the United States (1991), and in Japan (1992). Future CG International conferences are planned in Australia (1994), and in the United Kingdom (1995). COS also organizes each year Computer Animation in Geneva, an international workshop and Computer Generated Film Festival. Two new CGS events are planned in 1993: Pacific Graphics '93 in Seoul and MMM '93, an International Conference on Multi-Media MOdeling in Singapore. 624 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -How to protect against ischemia/reperfusion damage is one of the most urgent problems in medicine. It is known that ischemic damage can be attenuated by improving the oxygen balance of the ischemic heart, but the damage-producing mechanism is not yet fully understood. This book provides the latest information on the pathophysiology of ischemia/reperfusion damage and presents new ideas for more effective methods for protection. In the first two sections, the roles of such factors as various ions and phospholipids that modulate ischemia/reperfusion damage are explored, providing a clear and updated explanation of the mechanisms involved. In the third section, the myocardial and vascular remodeling procedure in hearts that have undergone ischemia/reperfusion is explained in terms of signal transduction, enabling a new understanding of the remodeling process. In the final section, a new approach to protection against ischemia/reperfusion damage is presented. 264 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent progress in brain science has been remarkable, especially with regard to advances in the area of neuroscience. Particularly in the past decade, there have been many important discoveries about signal transduction in the brain. With this background, biological research in affective disorders has become well developed in relation to neural signaling. However, this field is fairly hard to understand comprehensively, and there is relatively little integrative work with clinical psychiatry in spite of the involvement of a wide variety of scien tific disciplines. This monograph brings together up-to-date reviews from several young Japanese scientists who work in basic and clinical neuroscience. The intention is to explain in plain language the information that has evolved on signal transduction in terms of the biological abnormalities and mechanisms of anti depressants. The model shown on the cover (and on page 24) is intended to help the reader understand signal transduction in the brain and the patho physiology of affective disorders as well as the mechanisms of antidepressants. 160 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Coronary circulation research is advancing at a rapid rate. Not only are inno vative techniques for studying myocardial perfusion being developed, new mechanisms related to coronary blood flow control and mechanics are also being discovered. The progress in this field justifies an update in the form of this new monograph. The book is divided into the following sections: 'Measurement of Coronary Blood Flow and Assessment of Myocardial Per fusion' discusses advances in perfusion measurements in humans as well as nonradioactive microsphere methods. . 'Coronary Flow Dynamics' elucidates the effect of heart contraction on coronary flow, perfusion, and reserve distribution as well as systolic-diastolic interaction. Models-a frequent topic of debate-are used to quantify hypotheses. 'Models of Coronary Circulation' attempts to elucidate the concept of tissue pressure. 'Regulatory Mechanisms of Coronary circulation and its Clinical Relevance': N u.merous mechanisms affecting coronary flow have been defined and studied at the level of isolated vessels and whole organs. The chapters in this section provide an in-depth analysis of a selection of these mechanisms and their inter actions. 'Pathophysiology of Coronary Circulation in Ischemic Heart Disease' considers important aspects of factors which restrict perfusion of the myocardium in ischemic heart disease. An understanding these factors is of crucial importance in the management of patients. 'Small Vessel Disorder in Coronary Circulation' describes circulatory flow and how it can be influenced by drugs. 340 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Modern cell biology has brought improvements in therapy for advanced malignant diseases through immunomodulation, hematopoietic stem cell transplantation, and other advanced techniques. Collected here are selected papers from the Fifth International Symposium of Keio University for Life Sciences and Medicine on Cell Therapy.All chapters include innovative basic research for clinical application: immunotherapy, cancer vaccination, molecular biology of hematopoietic stem cells, stem cell processing, and gene therapy.The book is divided into three parts: Immunotherapy for malignant diseases; Hematopoietic stem cell biology and clinical application; and International collaboration in hematopoietic stem cell transplantation. Included in the third part is information on bone marrow registries from around the world.The book thus presents up-to-date information on biological and clinical aspects of treatment, with insight into the future of cell therapy. 260 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Synchrotron radiation has important applications in medical imaging, especially in such areas as intravenous coronary angiography, mammography, bronchography, and monochromatic computed tomography. In medicine, phase contrast imaging is a particularly exciting development, with the potential to become a new X-ray eye in the 21st century. To discuss these and related topics, medical doctors met with physicists and other researchers in Haga, Japan, in August 1997. This volume contains the proceedings of the International Workshop on Medical Applications of Synchrotron Radiation (HAGA 97), where practitioners from the world of medicine could communicate directly with researchers from the world of physics to discuss practical and theoretical aspects of medical imaging with synchrotron radiation. This volume, presenting the outcome of the discussions and presentations in the workshop, is a valuable resource to all who are interested in medical imaging and physics. 216 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Basic research on osteoarthritis has been carried out mainly from the his tological and biochemical aspects of the degenerating chondrocytes, collagen fibers, and matrix proteoglycans. Undue mechanical stress has been shown to be the principal factor in the initiation of osteoarthritis. Although the exact process by which mechanical stress leads to the total destruction of cartilage tissue remains unclear, several new research methods have enabled us to gain a deeper understanding of the process of degeneration. In October 1997, we organized an international symposium titled 'Ad vances in Osteoarthritis' in Kobe, with the main topics being updated re search, diagnosis, and treatment of osteoarthritis. The proceedings of the symposium are presented here in five sections: (1) Mechanical stress and reactions of chondrocytes, such as intracellular ion changes, changes in the cytoskeleton, intracellular messenger systems, release of gas mediators, and changes in electromechanical properties of cartilage; (2) Functional diagnosis of osteoarthritis by MR imaging, and using calpain and collagenase III as new cartilage markers; (3) Treatment with a promising simple washout technique and IL-1RA and MMP antagonists; (4) Cartilage repair by new grafting tech niques; and (5) Problems following total joint replacement. We sincerely hope that the advanced knowledge provided in this volume of proceedings will be valuable to our readers. 312 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Medically unexplained somatic symptoms are problematic in psychiatry, primary care settings, and other clinical areas. The burden they impose on health-care systems constitutes a significant public health problem. At the international symposium 'Rethinking Somatoform Disorders,' this problem was addressed by specialists working in somatoform disorders, psychiatric nosology, epidemiology, and biological and cross-cultural psychiatry. The meeting was the third of the Keio University International Symposia for Life Sciences and Medicine, in collaboration with the World Health Organization and the World Psychiatric Association. 312 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents basic information on material science (geochemistry, geophysics, geology, mineralogy, etc.), interaction between subsystem consisting earth system (atmosphere, hydrosphere, litho (geo) sphere, biosphere, humans) and in earth-planet system and evolution of earth-planetary system.The nature-humans interactions are described and new view on earth, planets and humans (integration of anthropocentrism and naturecentrism) are presented. 192 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Stroke is one of the major causes of disability in the world. Consequently, an effective rehabilitation regimen is the goal of specialists working in the field worldwide. The implementation of rehabilitation programs for the stroke patient is broad in scope and requires, first of all, an objective scientific evaluation method. In 1980 the World Health Organization developed the International Classification ofImpairments, Disabilities, and Handicaps. It categorized impairments and disabili ties on the basis of functional evaluation but took into account cultural and socioeco nomic factors when defining handicaps, thus making it difficult to use the same functional evaluation instrument for the three phenomena. In this monograph, experts in the treatment of stroke from Japan, the United States, and Europe share their ideas presented during the 31st Annual Convention of the Japanese Association of Rehabilitation Medicine held in June 1994. All the partici pants freely contributed their views on the functional assessment and prognosis of stroke patients. Indeed, their contributions shed light on possible breakthroughs in the future for the development of rehabilitation regimens for stroke patients. 164 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cerebral hypoxia/ischemia is a common cause of neurologic dysfunction following cardiopulmonary resuscitation. With the advent of aggressive resuscitatiQ,il ;m.ethods to treat cardiopulmonary arrest, more patients are surviving to live with posthypoxic/ postischemic neurologic syndromes. Thus, there is an urgent need to understand the basic aspects of the problem. This monograph consists of reviews from :s'c5ientists using advanced techniques for basic research into the molecular neurob~ology of the mechanisms and effects of cerebral hypoXia/ischemia, and from cliniciahs ~ctively involved in managing patients with these syndromes. The first five chapters contain several basic topics of neurobiology to help under stand brain function, followed by five chapters that deal with the mechanisms of cerebral hypoxia/ischemia and potential protective measures against it. The first chapter describes functional proteins in the presynaptic terminal which regulate transmitter release. This is followed by a chapter demonstrating the molecu lar structure and physiological function of the glutamate receptor channel, which may determine the rate and quantity of calcium ion influx into the nerve cell. The third chapter surveys the metabolic glutamate responses and the intracellular mechanisms believed to play an important role in pathogenesis of hypoxic/ischemic cell injury. The fourth chapter deals with long-term potentiation and drugs, the basis for under standing memory disturbance caused by cerebral hypoxia/ischemia. The fifth chapter describes distributions of nitric oxide synthase mRNAs in the brain, currently one of the most advanced fields in neurobiology. 176 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Global warming poses a serious threat to the quality of life in the 21st century. Taking Japan as an example, this book explains the anticipated impact of global warming on modern society-natural ecosystems; agriculture, forestry, and fisheries; water resources and environments; the infrastructure and socioeconomic system; and human health. The most recent scientific and technical information is presented by more than 30 prominent researchers who are assessing the potential impact of global warming on nature and society. The results of their research provide dramatic evidence of the urgency of the task faced by policy makers in responding to climate change. For scientists and government officials alike, this volume may be considered required reading. 260 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -For long-span bridges, wind action is a dominant factor in their safety and serviceability. A large number of long-span bridges have been built in Japan over the past 30 years, and tremendous amounts of research and technical development have been accomplished in wind-resistant design. This book is a compilation of the results of active research and development. Wind-resistant design standards generated in Japan are described in the first few chapters. Then comes information such as design wind speed, structural damping, wind tunnel tests, and analyses, which provide the basis of the design standards. Wind-induced vibrations and their control of girders, towers, cables, and other features are explained with examples of field measurements. Comprehensive listings of Japanese experience in vibration control are also presented. Because achieving particularly dynamic safety against wind is still not an easy task, these data and information will be valuable assets for the wind-engineering and bridge-engineering communities. 268 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The importance of the therapeutic time window for ischemic stroke has been widely accepted for a long time. Consequently, I have been thinking about the past, when the term 'brain attack,' which was reimported from the United States, began to spread by repetition. In the 1980s, I had made an enthusiastic study of acute-phase cerebral revascularization for ischemic stroke. At that time, we could cure only a quite lim ited number of patients, such as those who already were hospitalized or who, fortu nately, were brought to the hospital within a few hours from the onset of the stroke. RM Crowell, in his 1977 report! on cases of failure, had identified the consider able problems in acute-phase cerebral revascularization as diagnosis of tissue reversibility, brain-protective reagents or methods, and effective techniques for revascularization. I remember that we strongly endorsed his opinion. Recently, the basic study of stroke has advanced significantly, resulting in newly developed materials and new experimental techniques, which are introduced in this book. I hope that new basic knowledge will be clinically applied. 312 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Benign prostatic hyperplasia (BPH) is an age-related, nonmalignant condition that may lead to bothersome lower urinary tract symptoms. The standard treatment of BPH has been ordinary loop transurethral prostatectomy, but new therapies have been developed as a combined result of research, technological advances, and the cumulative experience of urological surgeons. Among the most promising therapeutic alternatives to ordinary loop resection are those that deliver topical or interstitial heat to prostatic tissue. Transurethral microwave thermotherapy, visual laser ablation with the Nd:YAG laser, high-intensity focused ultrasound, and transurethral electrovaporization are some of the techniques described in this book. These innovative procedures, employed by skilled urologists using state-of-the-art instruments, hold forth the promise of improved quality of life for BPH patients and represent significant advances in the field of urology. 216 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Schizophrenia is a serious mental disorder that can devastate the lives of patients and their families. The condition is chronic and may persist throughout patients' lives, disrupting education and work and greatly reducing the quality of life. Affecting nearly 0.8% of the population worldwide, schizophrenia is a serious public health problem demanding improved treatment. Recent progress in neuroscience and biological studies of schizophrenia is promising. However, to understand the concomitant behavioral characteristics and implement effective treatment programs, multifaceted approaches are required. 'Comprehensive Treatment of Schizophrenia' was the subject of the 8th Keio University International Symposium for Life Sciences and Medicine, held in Tokyo. From the symposium, 40 papers were chosen to be included here in nine sections covering the broad spectrum of recent clinical progress in the treatment of schizophrenia and allied disorders. 428 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A lot of economic problems can be formulated as constrained optimizations and equilibration of their solutions. Various mathematical theories have been supplying economists with indispensable machineries for these problems arising in economic theory. Conversely, mathematicians have been stimulated by various mathematical difficulties raised by economic theories. The series is designed to bring together those mathematicians who are seriously interested in getting new challenging stimuli from economic theories with those economists who seek effective mathematical tools for their researchers. The editorial board of this series comprises the following prominent economists and mathematicians: Managing Editors : S. Kusuoka (Univ. Tokyo), T. Maruyama (Keio Univ.); Editors : R. Anderson (U.C. Berkeley), C. Castaing (Univ. Montpellier), F. H. Clarke (Univ. Lyon I), G. Debreu (U.C. Berkeley), E. Dierker (Univ. Vienna), D. Duffie (Stanford Univ.), L.C. Evans (U.C. Berkeley), T. Fujimoto (Okayama Univ.), J.-M. Grandmont (CREST-CNRS), N. Hirano (Yokohama National Univ.), L. Hurwicz (Univ. of Minnesota), T. Ichiishi (Ohio State Univ.), A. Ioffe (Israel Institute of Technology), S. Iwamoto (Kyushu Univ.), K. Kamiya (Univ. Tokyo), K. Kawamata (Keio Univ.), N. Kikuchi (Keio Univ.), H. Matano (Univ. Tokyo), K. Nishimura (Kyoto Univ.), M. K. Richter (Univ. Minnesota), Y. Takahashi (Kyoto Univ.), M. Valadier (Univ. Montpellier II), M. Yano (Keio Univ). 200 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Urolithiasis is not only one of the most frequently encountered diseases at uro logical clinics; it is also the disorder whose treatment has shown the most rapid progress in the past decade. In that period, medicine has experienced a real revolution, characterized by minimally invasive treatments, improvement of the quality of life, and cost-effectiveness in treatment outcomes. In urology, the revolution started with the development of endoscopic retrograde treatment of urolithiasis in the upper urinary tract, which led to development of the percuta neous antegrade maneuver in the latter half of the 1970s. The most remarkable event occurred in 1982, when clinical use of extracorporeal shock wave lithotripsy was introduced by the Munich group, represented by Dr. Christian Chaussy, at the 18th Congress of the International Society of Urology in San Francisco. With the advent of these new strategies, open surgery for urolithiasis has all but dis appeared. Today, with the availability of new technology and equipment, guide lines for the treatment of urolithiasis have changed in all developed countries. It is quite timely that the Meeting of International Consultation on Urolithiasis will be held in Paris in June 2001 to establish international guidelines for urolithiasis. Looking through this textbook for urolithiasis, I was greatly impressed to learn that we have already drawn up some guidelines. The book includes all the updated advances of urolithiasis presented by the most prominent and experi enced urologists from all around the world. 200 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Researchers in recent decades have elucidated signal transduction in the retina and the function of the visual cortex. The highly flexible nature of neural circuits in the visual cortex especially during the critical period has been an interesting subject for studying neural plasticity and development. Recent advances in the visual neurosciences of the vertebrate retina and the visual cortex were discussed during the 12th Keio International Symposium for Life Science and Medicine, meeting jointly with Vision Forum 2002. Contributions to the symposium collected in this volume reflect the convergence of physiological, cell biological, molecular, mathematical, and clinical approaches. The book covers topics ranging from phototransduction to visual information processing in the primary visual cortex, and includes clinical studies on hereditary night blindness, creating a valuable source of information for researchers and clinicians in the visual neurosciences. 272 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -When I entered the field of allergy in the early 1970s, the standard textbook was a few hundred pages, and the specialty was so compact that texts were often authored entirely by a single individual and were never larger than one volume. Compare this with Allergy Frontiers: Epigenetics, Allergens, and Risk Factors, the present s- volume text with well over 150 contributors from throughout the world. This book captures the explosive growth of our specialty since the single-author textbooks referred to above. The unprecedented format of this work lies in its meticulous attention to detail yet comprehensive scope. For example, great detail is seen in manuscripts dealing with topics such as 'Exosomes, naturally occurring minimal antigen presenting units' and 'Neuropeptide S receptor 1 (NPSR1), an asthma susceptibility gene.' The scope is exemplified by the unique approach to disease entities normally dealt with in a single chapter in most texts. For example, anaphylaxis, a topic usually confined to one chapter in most textbooks, is given five chapters in Allergy Frontiers. This approach allows the text to employ multiple contributors for a single topic, giving the reader the advantage of being introduced to more than one vi- point regarding a single disease. 344 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Interface oral health science is founded on the concept that healthy oral function is maintained by biological and biomechanical harmony between three systems: oral tissues, parasitic oral microorganisms, and biomaterials. On that basis, dental caries, periodontal disease, and temporomandibular joint disorders may be regarded as interface disorders that result from a disruption in the intact interface of these systems. Interface oral health science encompasses the fields of dentistry and dental medicine, but also extends to general medicine, agriculture, biomaterial science, bioengineering, and pharmacology. This book is a compendium of the research presented at symposiums held in 2011 by the Tohoku University Graduate School of Dentistry and by The Forsyth Institute. This publication is intended to drive the progress of dental and craniofacial sciences, pointing the way for dental research for future generations. 444 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -When I entered the field of allergy in the early 1970s, the standard textbook was a few hundred pages, and the specialty was so compact that texts were often authored entirely by a single individual and were never larger than one volume. Compare this with Allergy Frontiers: Epigenetics, Allergens, and Risk Factors, the present s- volume text with well over 150 contributors from throughout the world. This book captures the explosive growth of our specialty since the single-author textbooks referred to above. The unprecedented format of this work lies in its meticulous attention to detail yet comprehensive scope. For example, great detail is seen in manuscripts dealing with topics such as 'Exosomes, naturally occurring minimal antigen presenting units' and 'Neuropeptide S receptor 1 (NPSR1), an asthma susceptibility gene.' The scope is exemplified by the unique approach to disease entities normally dealt with in a single chapter in most texts. For example, anaphylaxis, a topic usually confined to one chapter in most textbooks, is given five chapters in Allergy Frontiers. This approach allows the text to employ multiple contributors for a single topic, giving the reader the advantage of being introduced to more than one vi- point regarding a single disease. 784 pp. Englisch.