springer japan springer japan feb 2015 (15 résultats)

Buch. Etat : Neu. Neuware -This book brings together leading international experts to discuss recent advances in functional studies on key proteins and protein complexes involved in each synaptic vesicle phase. These include proteins that control the final step of neurotransmitter release, in response to a neural signal, and the first step of vesicle endocytosis, which helps maintain stable neurotransmitter release in response to unceasing neural signals arriving at presynaptic terminals.Neural networks transmit input and output signals of action potentials using chemical synapses. The strength of the signal from one to another neuron can be tuned by the neural signal itself as it induces Ca2+ entry and by other neurons¿ signals that modify Ca2+ entry through voltage-gated Ca2+ channels at the active zone, where chemical neurotransmitters are released from synaptic vesicles via exocytosis. Synaptic vesicles are docked and primed at the active zone prior to exocytosis and are endocytosed after exocytosis for reuse at a small presynaptic terminal. Recycled vesicles are refilled with transmitters and stored for a future round of exocytosis. Thus, synaptic vesicles in presynaptic terminals go through various phases. Each vesicle phase is well orchestrated by numerous proteins and advance step-by-step with neural activities.The fine regulations of synaptic vesicle phases by numerous proteins is an exciting subject, and systematic, well-organized explanations in this book will help the reader easily learn about complicated molecular mechanisms in presynaptic terminals.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 380 pp. Englisch.

Buch. Etat : Neu. Neuware -This book is based on the author¿s work at the Double Chooz Experiment, from 2010 to 2013, the goal of which was to search for electronic anti-neutrino disappearance close to nuclear power plant facilities as a result of neutrino oscillation. Starting with a brief review of neutrino oscillation and the most important past experimental findings in this field, the author subsequently provides a full and detailed description of a neutrino detector, from simulation aspects to detection principles, as well as the data analysis procedure used to extract the oscillation parameters. The main results in this book are 1) an improvement on the mixing angle, ¿13, uncertainty by combining two data-sets from neutrino event selection: neutron capture on gadolinium and on hydrogen; and 2) the first measurement of the effective squared mass difference by combining the current reactor neutrino experimental data from Daya Bay, Double Chooz and RENO and taking advantage of their different reactor-to-detector distances. The author explains how these methods of combining data can be used toestimate these two values. Each method results in the best possible sensitivity for the oscillation parameters with regard to reactor neutrinos. They can be used as a standard method on the latest data releases from the current experiments.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 208 pp. Englisch.

Buch. Etat : Neu. Neuware -In this book the authors describe how they reproduced the redox functions of biocatalysts artificially. It includes the introduction and discussion of synthetic reactions via electron transfer, hybrid ¿-conjugated systems, and biorganometallic conjugates as novel redox systems. The work was conducted in pioneering fields based on redox systems, in synthetic organic chemistry, synthetic materials chemistry, and bioorganometallic chemistry. The step-by-step process is illustrated by the three major parts of the book:redox reactions (selective synthetic methods using metal-induced redox reactions), redox systems (design and redox function of conjugated complexes with polyanilines or quinonediimines and molecular bowl sumanene), anddesign of bioorganometallic conjugates to induce chirality-organized structures (bio-related structurally controlled systems). This systematic and up-to-date description will be of special interest to graduate students who are meeting the new challenges of chemistry, as well as to post-doctoral researchers and other practicing chemists in both academic and industrial settings.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 160 pp. Englisch.

Buch. Etat : Neu. Neuware -This book comprehensively covers the latest information about ventricular¿vascular morphology and function in congenital heart disease (CHD) assessed by various innovative methodologies.Anatomical (morphological) abnormalities in CHD are generally accompanied with abnormal loading conditions, which, in turn, cause ventricular and vascular functional impairments. The functional impairments may also exist independently of the anatomical abnormalities. These two (morphological and functional abnormalities) importantly interact to determine underlying pathophysiology and generate clinical symptoms in CHD. Therefore, detailed and precise assessment of morphology and function is essential to better understand and treat this disease. Recent advances in technology have provided useful tools for this purpose, and novel findings are accumulating. The information contained here will provide researchers and clinicians with invaluable knowledge in this field.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 216 pp. Englisch.

Buch. Etat : Neu. Neuware -There is more to biological rhythms than circadian clocks. This book aims at promoting the exciting potential of a deeper understanding of circannual, circatidal, and circalunar clocks. It highlights new developments, summarizes existing knowledge, and integrates different perspectives with the tools and ideas of diverse fields of current biology.For predominantly pragmatic reasons, research in recent decades was mostly concerned with circadian clocks. Clocks on other timescales, however, have been largely neglected and therefore still appear 'enigmatic'. Thanks to the rapid development of methods in molecular biology as well as in ecology, we are now able to re-approach these clocks. Laboratories around the world are showing fresh interest and substantial progress is being made in many independent projects.The book's two sections address the moon-derived circatidal, circasemilunar, and lunar cycles on the one hand (10 chapters), and the sun-derived circannual cycleson the other (6 chapters). This work brings together authors with an expansive array of expertise and study systems, ranging from tidal cycles of marine invertebrates to annual cycles of birds and mammals, and from behavioral to genetic and epigenetic backgrounds. While great challenges remain to be mastered, the book aims at conveying the excitement of unraveling, broadly, the rhythms of life.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 372 pp. Englisch.

Buch. Etat : Neu. Neuware -Traditionally, Lie theory is a tool to build mathematical models for physical systems. Recently, the trend is towards geometrization of the mathematical description of physical systems and objects. A geometric approach to a system yields in general some notion of symmetry which is very helpful in understanding its structure. Geometrization and symmetries are meant in their widest sense, i.e., representation theory, algebraic geometry, infinite-dimensional Lie algebras and groups, superalgebras and supergroups, groups and quantum groups, noncommutative geometry, symmetries of linear and nonlinear PDE, special functions, and others. Furthermore, the necessary tools from functional analysis and number theory are included. This is a big interdisciplinary and interrelated field.Samples of these fresh trends are presented in this volume, based on contributions from the Workshop 'Lie Theory and Its Applications in Physics' held near Varna (Bulgaria) in June 2013.This book is suitable for a broad audience of mathematicians, mathematical physicists, and theoretical physicists and researchers in the field of Lie Theory.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 588 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study of poverty dynamics is important for effective poverty alleviation policies because the changes in income poverty are also accompanied by changes in socioeconomic factors such as literacy, gender parity in school, health care, infant mortality, and asset holdings. In order to examine the dynamics of poverty, information from 1,212 households in 32 rural villages in Bangladesh was collected in December 2004 and December 2009. This book reports the analytical results from quantitative and qualitative surveys from the same households at two points of time, which yielded the panel data for understanding the changes in situations of poverty.Efforts have been made to include the most recent research from diverse disciplines including economics, statistics, anthropology, education, health care, and vulnerability study. Specifically, findings from logistic regression analysis, polychoric principal component analysis, kernel density function, income mobility with the help of the Markov chain model, and child nutrition status from anthropometric measures have been presented.Asset holdings and liabilities of the chronically poor as well as those of three other economic groups (the descending non-poor, the ascending poor, and the non-poor) are analyzed statistically. The degrees of vulnerability to poverty are examined by years of schooling, landholding size, gender of household head, social capital, and occupation. The multiple logistic regression model was used to identify important risk factors for a household's vulnerability.In 2009, some of the basic characteristics of the chronically poor were: higher percentage and number of female-headed households, higher dependency ratio, lower levels of education, fewer years of schooling, and limited employment. There was a low degree of mobility of households from one poverty status to another in the period 2004-2009, implying that the process of economic development and high economic growth in the macroeconomy during this time failed to improve the poverty situation in rural Bangladesh. 276 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book comprehensively covers the latest information about ventricular-vascular morphology and function in congenital heart disease (CHD) assessed by various innovative methodologies.Anatomical (morphological) abnormalities in CHD are generally accompanied with abnormal loading conditions, which, in turn, cause ventricular and vascular functional impairments. The functional impairments may also exist independently of the anatomical abnormalities. These two (morphological and functional abnormalities) importantly interact to determine underlying pathophysiology and generate clinical symptoms in CHD. Therefore, detailed and precise assessment of morphology and function is essential to better understand and treat this disease. Recent advances in technology have provided useful tools for this purpose, and novel findings are accumulating. The information contained here will provide researchers and clinicians with invaluable knowledge in this field. 216 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this book the authors describe how they reproduced the redox functions of biocatalysts artificially. It includes the introduction and discussion of synthetic reactions via electron transfer, hybrid pi-conjugated systems, and biorganometallic conjugates as novel redox systems. The work was conducted in pioneering fields based on redox systems, in synthetic organic chemistry, synthetic materials chemistry, and bioorganometallic chemistry. The step-by-step process is illustrated by the three major parts of the book: redox reactions (selective synthetic methods using metal-induced redox reactions), redox systems (design and redox function of conjugated complexes with polyanilines or quinonediimines and molecular bowl sumanene), and design of bioorganometallic conjugates to induce chirality-organized structures (bio-related structurally controlled systems). This systematic and up-to-date description will be of special interest to graduate students who are meeting the new challenges of chemistry, as well as to post-doctoral researchers and other practicing chemists in both academic and industrial settings. 160 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book brings together leading international experts to discuss recent advances in functional studies on key proteins and protein complexes involved in each synaptic vesicle phase. These include proteins that control the final step of neurotransmitter release, in response to a neural signal, and the first step of vesicle endocytosis, which helps maintain stable neurotransmitter release in response to unceasing neural signals arriving at presynaptic terminals.Neural networks transmit input and output signals of action potentials using chemical synapses. The strength of the signal from one to another neuron can be tuned by the neural signal itself as it induces Ca2+ entry and by other neurons' signals that modify Ca2+ entry through voltage-gated Ca2+ channels at the active zone, where chemical neurotransmitters are released from synaptic vesicles via exocytosis. Synaptic vesicles are docked and primed at the active zone prior to exocytosis and are endocytosed after exocytosis for reuse at a small presynaptic terminal. Recycled vesicles are refilled with transmitters and stored for a future round of exocytosis. Thus, synaptic vesicles in presynaptic terminals go through various phases. Each vesicle phase is well orchestrated by numerous proteins and advance step-by-step with neural activities.The fine regulations of synaptic vesicle phases by numerous proteins is an exciting subject, and systematic, well-organized explanations in this book will help the reader easily learn about complicated molecular mechanisms in presynaptic terminals. 380 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is based on the author's work at the Double Chooz Experiment, from 2010 to 2013, the goal of which was to search for electronic anti-neutrino disappearance close to nuclear power plant facilities as a result of neutrino oscillation. Starting with a brief review of neutrino oscillation and the most important past experimental findings in this field, the author subsequently provides a full and detailed description of a neutrino detector, from simulation aspects to detection principles, as well as the data analysis procedure used to extract the oscillation parameters. The main results in this book are 1) an improvement on the mixing angle, th13, uncertainty by combining two data-sets from neutrino event selection: neutron capture on gadolinium and on hydrogen; and 2) the first measurement of the effective squared mass difference by combining the current reactor neutrino experimental data from Daya Bay, Double Chooz and RENO and taking advantage of their different reactor-to-detector distances. The author explains how these methods of combining data can be used to estimate these two values. Each method results in the best possible sensitivity for the oscillation parameters with regard to reactor neutrinos. They can be used as a standard method on the latest data releases from the current experiments. 208 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -The study of poverty dynamics is important for effective poverty alleviation policies because the changes in income poverty are also accompanied by changes in socioeconomic factors such as literacy, gender parity in school, health care, infant mortality, and asset holdings. In order to examine the dynamics of poverty, information from 1,212 households in 32 rural villages in Bangladesh was collected in December 2004 and December 2009. This book reports the analytical results from quantitative and qualitative surveys from the same households at two points of time, which yielded the panel data for understanding the changes in situations of poverty.Efforts have been made to include the most recent research from diverse disciplines including economics, statistics, anthropology, education, health care, and vulnerability study. Specifically, findings from logistic regression analysis, polychoric principal component analysis, kernel density function, income mobility with the help of the Markov chain model, and child nutrition status from anthropometric measures have been presented.Asset holdings and liabilities of the chronically poor as well as those of three other economic groups (the descending non-poor, the ascending poor, and the non-poor) are analyzed statistically. The degrees of vulnerability to poverty are examined by years of schooling, landholding size, gender of household head, social capital, and occupation. The multiple logistic regression model was used to identify important risk factors for a household¿s vulnerability.In 2009, some of the basic characteristics of the chronically poor were: higher percentage and number of female-headed households, higher dependency ratio, lower levels of education, fewer years of schooling, and limited employment. There was a low degree of mobility of households from one poverty status to another in the period 2004-2009, implying that the process of economic development and high economicgrowth in the macroeconomy during this time failed to improve the poverty situation in rural Bangladesh.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 276 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Traditionally, Lie theory is a tool to build mathematical models for physical systems. Recently, the trend is towards geometrization of the mathematical description of physical systems and objects. A geometric approach to a system yields in general some notion of symmetry which is very helpful in understanding its structure. Geometrization and symmetries are meant in their widest sense, i.e., representation theory, algebraic geometry, infinite-dimensional Lie algebras and groups, superalgebras and supergroups, groups and quantum groups, noncommutative geometry, symmetries of linear and nonlinear PDE, special functions, and others. Furthermore, the necessary tools from functional analysis and number theory are included. This is a big interdisciplinary and interrelated field.Samples of these fresh trends are presented in this volume, based on contributions from the Workshop 'Lie Theory and Its Applications in Physics' held near Varna (Bulgaria) in June 2013.This book is suitable for a broad audience of mathematicians, mathematical physicists, and theoretical physicists and researchers in the field of Lie Theory. 588 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -There is more to biological rhythms than circadian clocks. This book aims at promoting the exciting potential of a deeper understanding of circannual, circatidal, and circalunar clocks. It highlights new developments, summarizes existing knowledge, and integrates different perspectives with the tools and ideas of diverse fields of current biology.For predominantly pragmatic reasons, research in recent decades was mostly concerned with circadian clocks. Clocks on other timescales, however, have been largely neglected and therefore still appear 'enigmatic'. Thanks to the rapid development of methods in molecular biology as well as in ecology, we are now able to re-approach these clocks. Laboratories around the world are showing fresh interest and substantial progress is being made in many independent projects. The book's two sections address the moon-derived circatidal, circasemilunar, and lunar cycles on the one hand (10 chapters), and the sun-derived circannual cycles on the other (6 chapters). This work brings together authors with an expansive array of expertise and study systems, ranging from tidal cycles of marine invertebrates to annual cycles of birds and mammals, and from behavioral to genetic and epigenetic backgrounds. While great challenges remain to be mastered, the book aims at conveying the excitement of unraveling, broadly, the rhythms of life. 372 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book describes the anatomy of the posterior fossa, together with the main associated surgical techniques, which are detailed in numerous photographs and step-by-step color illustrations.The book presents approaches and surgical techniques such as the trans-cerebellomedullary fissure approach and its variation to the fourth ventricle, as well as the cerebellomedullary cistern, infratentorial lateral supracerebellar approach to the fifth cranial nerve in the upper cerebellopontine angle, infrafloccular approach to the root exit zone of the seventh cranial nerve, transcondylar fossa approach through the lateral part of the foramen magnum, and the stitched sling retraction technique utilized during microvascular decompression procedures for trigeminal neuralgia and hemifacial spasm. It also describes in detail the bridging veins of the posterior fossa, especially the petrosal vein, and bridging veins to the tentorial sinuses, which can block approaches to the affected area.Each chapter begins with an anatomical description of the posterior fossa, after which the respective surgical approaches are explained in an easy-to-follow manner.The original Japanese version of this work was published 8 years ago, and has established itself as a trusted guide, especially among young neurosurgeons who need to study various surgical approaches and techniques. In the course of being translated into English, some sections have been revised and new information has been added. The author hopes that the book will help neurosurgeons around the world perform safer operations with confidence. 340 pp. Englisch.