springer us apr 1987 (17 résultats)

Buch. Etat : Neu. Neuware -As a division of the School of Medicine at the University of North Carolina at ChapeI Hili, TEACCH has always been involved in the latest biological research on autism and related developmental disabilities. However, until now there has not been sufficient information to justify aseparate volume on this most important topic. Recent advances both in our under standing of the brain and in the technology to facilitate the measurement of neurological functioning have stimulated significant growth, which is reflected in this volume. As with the preceding books in this series, Current Issues in Autism, this volume is based on one of the annual TEACCH conferences held in ChapeI Hili each May. The books are not simply published proceedings of the conference papers, however. lnstead, conference participants are asked to develop chapters around their presentations, and other international experts whose work is beyond the scope of the conference, but related to the major theme, are asked to contribute as weil. These volumes are intended to provide the most current knowledge and professional practice available to us concerning major issues in autism.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 444 pp. Englisch.

Buch. Etat : Neu. Neuware -Recent years have seen enormous advances in the field of protein and peptide engineering and a greater understanding in the way in which biological response modifiers function in the body. It is now possible through the use of recombinant DNA techniques, or by solid phase protein synthesis, to produce significant quantities of a wide variety of regulatory agents that are therapeutically applicable. The list of these response modifiers expands almost daily to include interferons, macrophage activation factors, neuropeptides and agents that may have potential in cardiovascular disease, inflammation, contraception etc. Prospects to use some of these materials in medicine have reached the stage where products have either been approved by regulatory authorities or are the subject of applications as investigatory drugs or as new therapeutic agents. In some uses the pertinent agent will be administered on an acute basis in the form of a simple injection, as, for example, the use of a tissue plasminogen activator for the treatment of coronary infarct. In other cases regulatory proteins and peptides are indicated for chronic therapy and here they will need to be administered by an appropriate delivery system. Unfortunately, the research on delivery systems for peptides and proteins has not kept pace with the rapid progress in biotechnology and, consequently, there are presently few systems that are entirely appropriate for the administration of macromolecular drugs according to complex dosage regimens, (eg intermittent and pulsed therapy). Furthermore essential pharmacokinetic and pharmacodynamic data may be missing.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 384 pp. Englisch.

Buch. Etat : Neu. Neuware Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 420 pp. Englisch.

Buch. Etat : Neu. Neuware.

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -In various fields of science, notably in physics and biology, one is con fronted with periodic phenomena having a remarkable temporal structure: it is as if certain systems are periodically reset in an initial state. A paper of Van der Pol in the Philosophical Magazine of 1926 started up the investigation of this highly nonlinear type of oscillation for which Van der Pol coined the name 'relaxation oscillation'. The study of relaxation oscillations requires a mathematical analysis which differs strongly from the well-known theory of almost linear oscillations. In this monograph the method of matched asymptotic expansions is employed to approximate the periodic orbit of a relaxation oscillator. As an introduction, in chapter 2 the asymptotic analysis of Van der Pol's equation is carried out in all detail. The problem exhibits all features characteristic for a relaxation oscillation. From this case study one may learn how to handle other or more generally formulated relaxation oscillations. In the survey special attention is given to biological and chemical relaxation oscillators. In chapter 2 a general definition of a relaxation oscillation is formulated.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As a division of the School of Medicine at the University of North Carolina at ChapeI Hili, TEACCH has always been involved in the latest biological research on autism and related developmental disabilities. However, until now there has not been sufficient information to justify aseparate volume on this most important topic. Recent advances both in our under standing of the brain and in the technology to facilitate the measurement of neurological functioning have stimulated significant growth, which is reflected in this volume. As with the preceding books in this series, Current Issues in Autism, this volume is based on one of the annual TEACCH conferences held in ChapeI Hili each May. The books are not simply published proceedings of the conference papers, however. lnstead, conference participants are asked to develop chapters around their presentations, and other international experts whose work is beyond the scope of the conference, but related to the major theme, are asked to contribute as weil. These volumes are intended to provide the most current knowledge and professional practice available to us concerning major issues in autism. 444 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Work occupies a pivotal role in the daily activities and over the course of a lifetime of members of modern societies. In anticipation, work influ ences education and training; it has much to do with shaping current earned income and status in the community; and in retrospect, it influ ences retirement income and activities. It is a powerful force affecting personal associations. In our society work is deeply encased in moral and religious values: As Poor Richard says, A Life of Leisure and a Life of Laziness are two Things. Do you imagine that Sloth will afford you more Comfort than Labour No, for as Poor Richard says: . Industry gives Comfort, and Plenty and Respect. Study to show thyself approved unto God a workman that needeth not to be ashamed. But few words have as many different meanings and nuances as 'work': to forge or to shape, to stir or to knead, to solve, to exploit, to practice trickery for some end, to excite or to provoke, to persuade or to influence, to toil, and the like. A need for precision in meaning is requisite with respect to work, not only in common discourse, but, even more so, in scholarly communication. 272 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Work occupies a pivotal role in the daily activities and over the course of a lifetime of members of modern societies. In anticipation, work influ ences education and training; it has much to do with shaping current earned income and status in the community; and in retrospect, it influ ences retirement income and activities. It is a powerful force affecting personal associations. In our society work is deeply encased in moral and religious values: As Poor Richard says, A Life of Leisure and a Life of Laziness are two Things. Do you imagine that Sloth will afford you more Comfort than Labour No, for as Poor Richard says: . Industry gives Comfort, and Plenty and Respect. Study to show thyself approved unto God a workman that needeth not to be ashamed. But few words have as many different meanings and nuances as 'work': to forge or to shape, to stir or to knead, to solve, to exploit, to practice trickery for some end, to excite or to provoke, to persuade or to influence, to toil, and the like. A need for precision in meaning is requisite with respect to work, not only in common discourse, but, even more so, in scholarly communication.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 272 pp. Englisch.

Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Tables of Contents.- 1. Stationary point processes and Palm probabilities.- 1. Stationary marked point processes.- 1.1. The canonical space of point processes on IR.- 1.2. Stationary point processes.- 1.3. Stationary marked point processes.- 1.4. Two properties of stationary point processes.- 2. Intensity.- 2.1. Intensity of a stationary point process.- 2.2. Intensity measure of a stationary marked point process.- 3. Palm probability.- 3.1. Mecke¿ s definition.- 3.2. Invariance of the Palm probability.- 3.3. Campbell¿ s formula.- 3.4. The exchange formula (or cycle formula) and Wald¿ s equality.- 4. From Palm probability to stationary probability.- 4.1. The inversion formula.- 4.2. Feller¿ s paradox.- 4.3. The mean value formulae.- 4.4. The inverse construction.- 5. Examples.- 5.1. Palm probability of a superposition of independent point processes.- 5.2. Palm probability associated with selected marks.- 5.3. Palm probability of selected transitions of a Markov chain.- 6. Local aspects of Palm probability.- 6.1. Korolyuk and Dobrushin¿ s infinitesimal estimates.- 6.2. Conditioning at a point.- 7. Characterization of Poisson processes.- 7.1. Predictable -fields.- 7.2. Stochastic intensity and Radon-Nikodym derivatives.- 7.3. Palm view at Watanabe¿ s characterization theorem.- 8. Ergodicity of point processes.- 8.1. Invariant events.- 8.2. Ergodicity under the stationary probability and its Palm probability.- 8.3. The cross ergodic theorem.- References for Part 1: Palm probabilities.- 2. Stationary queueuing systems.- 1. The G/G/1/ queue : construction of the customer stationary state.- 1.1. Loynes¿ problem.- 1.2. Existence of a finite stationary load.- 1.3. Uniqueness of the stationary load.- 1.4. Construction points.- 1.5. Initial workload and long term behaviour.- 2. Formulae for the G/G/1/ queue.- 2.1. Construction of the time-stationary workload.- 2.2. Little¿ s formulae: the FIFO case.- 2.3. Probability of emptiness.- 2.4. Takacs formulae.- 3. The G/G/s/ queue.- 3.1. The ordered workload vector.- 3.2. Existence of a finite stationary workload vector.- 3.3. Construction points.- 3.4. The busy cycle formulae.- 4. The G/G/1/0 queue.- 4.1. Definition and examples.- 4.2. Construction of an enriched probability space.- 4.3. Construction of a stationary solution.- 5. Other queueing systems.- 5.1. The G/G/ pure delay system.- 5.2. The G/G/1/ queue in random environment.- 5.3. Priorities in G/G/1/ : the vector of residual service times.- 5.4. Optimality properties of the SPRT rule.- 6. The Bedienungssysteme.- 6.1. The mechanism and the input.- 6.2. A heuristic description of the dynamics.- 6.3. The initial generalized state.- 6.4. The evolution.- 6.5. Examples.- 7. The insensitivity balance equations.- 7.1. Stability and regularity assumptions.- 7.2. Insensitivity balance equations.- 7.3. Examples.- 7.4. Assumption on the input.- 7.5. Two immediate consequences of the insensitivity balance equations.- 8. The insensitivity theorem.- 8.1. The Palm version.- 8.2. From Palm to stationary.- 8.3. The stationary version and Matthes product form.- 9. Insensitivity balance equations are necessary for insensitivity.- 9.1. The converse theorem.- 9.2. The method of stages.- 9.3. Proof of the converse theorem.- 9.4. Example.- 10. Poisson streams.- 10.1. Privileged transitions.- 10.2. Sufficient conditions for Poissonian streams.- 1. Change of scale.- 2. Proof of insensitivity.- 3. The transition marks.- 4. Proof of (8.3.5).- 5. Proof of (9.1.3).- 6. Proof of the converse theorem in the general case.- References for part 2: Stationary queueing systems.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 120 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 420 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent years have seen enormous advances in the field of protein and peptide engineering and a greater understanding in the way in which biological response modifiers function in the body. It is now possible through the use of recombinant DNA techniques, or by solid phase protein synthesis, to produce significant quantities of a wide variety of regulatory agents that are therapeutically applicable. The list of these response modifiers expands almost daily to include interferons, macrophage activation factors, neuropeptides and agents that may have potential in cardiovascular disease, inflammation, contraception etc. Prospects to use some of these materials in medicine have reached the stage where products have either been approved by regulatory authorities or are the subject of applications as investigatory drugs or as new therapeutic agents. In some uses the pertinent agent will be administered on an acute basis in the form of a simple injection, as, for example, the use of a tissue plasminogen activator for the treatment of coronary infarct. In other cases regulatory proteins and peptides are indicated for chronic therapy and here they will need to be administered by an appropriate delivery system. Unfortunately, the research on delivery systems for peptides and proteins has not kept pace with the rapid progress in biotechnology and, consequently, there are presently few systems that are entirely appropriate for the administration of macromolecular drugs according to complex dosage regimens, (eg intermittent and pulsed therapy). Furthermore essential pharmacokinetic and pharmacodynamic data may be missing. 384 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The intention of the series Developments in Veterinary Virology is to provide monographs dealing with the major animal viral diseases. Each volume will include the latest achievements in fundamental research and practical applications and should be readable for people from various disciplines and different backgrounds. The multi-author approach provides the best opportunity to keep each chapter at the highest level and makes the composition of the volumes manageable to the editors. This monograph on Avian Leukosis presents comprehensive reviews on the recent history of avian retrovirus research, on epizootiological, virological, pathological aspects, on tumor induction, the immune response to avian retro viruses, virus-cell interactions and on techniques for diagnosis. The volume deals mainly with exogenous avian leukosis virus (ALV) infections, but one chapter is entirely devoted to endogenous avian leukemia virus. Molecular biology aspects are confined to various oncogenes and to lymphoma induction since retroviruses, including those specific for avian species, have recently been described in detail in the Cold Spring Harbor Laboratory series 'Molecular Biology of Tumor Viruses'. Two chapters are devoted to the practical application of insights obtained from avian leukosis research: influences of AL V infection on production performance and eradication procedures. 308 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -When I first proposed a series entitled Current Mammalogy to the pub lishers, they were reluctant to undertake such a project because they viewed the field of mammology as overly fragmented. At first I found this idea to be difficult to accept; however, upon reflection, I came near to agreeing with it. Although many of us work on mammals, we gen erally feel more allegiance to our specialties, such as systematics, ge netics, cytogenetics, ecology, behavior, pest control, paleontology, wildlife management, primatology, and marine mammalogy, than we do to the general field of mammalogy. However, rather than becoming discour aged from pursuing this project, I became more certain than ever that a series such as Current Mammalogy was needed. We hope to make this series a place where specialists can present their ideas not only to other members of their specialty, but to those outside the area as well. Hopefully, this exchange of ideas will be a mutually beneficial exercise. The Editorial Board of Current Mammalogy has decided to keep the range of subjects in each volume as broad as possible rather than concentrating on one or two topics, in the hope that this will keep the series as useful as possible to the broadest range of readers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 544 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -The intention of the series Developments in Veterinary Virology is to provide monographs dealing with the major animal viral diseases. Each volume will include the latest achievements in fundamental research and practical applications and should be readable for people from various disciplines and different backgrounds. The multi-author approach provides the best opportunity to keep each chapter at the highest level and makes the composition of the volumes manageable to the editors. This monograph on Avian Leukosis presents comprehensive reviews on the recent history of avian retrovirus research, on epizootiological, virological, pathological aspects, on tumor induction, the immune response to avian retro viruses, virus-cell interactions and on techniques for diagnosis. The volume deals mainly with exogenous avian leukosis virus (ALV) infections, but one chapter is entirely devoted to endogenous avian leukemia virus. Molecular biology aspects are confined to various oncogenes and to lymphoma induction since retroviruses, including those specific for avian species, have recently been described in detail in the Cold Spring Harbor Laboratory series 'Molecular Biology of Tumor Viruses'. Two chapters are devoted to the practical application of insights obtained from avian leukosis research: influences of AL V infection on production performance and eradication procedures.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Throughout the past 30 years, there have been significant developments in theory and research relating family variables to various psychopathologies. The potential importance of such efforts is obviously great, given the implications that reliable and valid findings would hold for treatment and preventive inter ventions across a variety of settings and populations. The purpose of this volume is to present a critical evaluation of this field of inquiry through a detailed assessment of the theoretical perspectives, the methodological issues, and the substantive findings that have characterized family studies of psychopathology during the past several decades. The book is divided into four parts, each con taining contributions from leading researchers and theorists in the field. The first part, 'Background,' presents a review of the major streams of influence that have shaped the development and the present character of the field. The second part, 'Conceptual Foundations,' contains presentations of gen eral models and orientations relevant to family studies of psychopathology. In most cases, a particular theoretical perspective provides the primary underpin ning of the approach, the exception to this format being the family model of David Reiss based on the concept of the family paradigm. The major objective of this part is to present a broad yet detailed set of chapters that address the conceptual status of the field. It is hoped that this material will provide a rich background against which subsequent discussions of specific theories, methods, and findings can be more fully appreciated.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 688 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Throughout the past 30 years, there have been significant developments in theory and research relating family variables to various psychopathologies. The potential importance of such efforts is obviously great, given the implications that reliable and valid findings would hold for treatment and preventive inter ventions across a variety of settings and populations. The purpose of this volume is to present a critical evaluation of this field of inquiry through a detailed assessment of the theoretical perspectives, the methodological issues, and the substantive findings that have characterized family studies of psychopathology during the past several decades. The book is divided into four parts, each con taining contributions from leading researchers and theorists in the field. The first part, 'Background,' presents a review of the major streams of influence that have shaped the development and the present character of the field. The second part, 'Conceptual Foundations,' contains presentations of gen eral models and orientations relevant to family studies of psychopathology. In most cases, a particular theoretical perspective provides the primary underpin ning of the approach, the exception to this format being the family model of David Reiss based on the concept of the family paradigm. The major objective of this part is to present a broad yet detailed set of chapters that address the conceptual status of the field. It is hoped that this material will provide a rich background against which subsequent discussions of specific theories, methods, and findings can be more fully appreciated. 688 pp. Englisch.

Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -When I first proposed a series entitled Current Mammalogy to the pub lishers, they were reluctant to undertake such a project because they viewed the field of mammology as overly fragmented. At first I found this idea to be difficult to accept; however, upon reflection, I came near to agreeing with it. Although many of us work on mammals, we gen erally feel more allegiance to our specialties, such as systematics, ge netics, cytogenetics, ecology, behavior, pest control, paleontology, wildlife management, primatology, and marine mammalogy, than we do to the general field of mammalogy. However, rather than becoming discour aged from pursuing this project, I became more certain than ever that a series such as Current Mammalogy was needed. We hope to make this series a place where specialists can present their ideas not only to other members of their specialty, but to those outside the area as well. Hopefully, this exchange of ideas will be a mutually beneficial exercise. The Editorial Board of Current Mammalogy has decided to keep the range of subjects in each volume as broad as possible rather than concentrating on one or two topics, in the hope that this will keep the series as useful as possible to the broadest range of readers. 548 pp. Englisch.