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Edité par LAP LAMBERT Academic Publishing, 2012
ISBN 10 : 3848428504ISBN 13 : 9783848428502
Vendeur : Lucky's Textbooks, Dallas, TX, Etats-Unis
Livre
Etat : New.
Edité par LAP LAMBERT Academic Publishing, 2012
ISBN 10 : 3848428504ISBN 13 : 9783848428502
Vendeur : PBShop.store US, Wood Dale, IL, Etats-Unis
Livre impression à la demande
PAP. Etat : New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Edité par LAP LAMBERT Academic Publishing, 2012
ISBN 10 : 3848428504ISBN 13 : 9783848428502
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
Livre impression à la demande
Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Here we present evidence that the transcription factor Teashirt (Tsh) has a role in cell proliferation in Drosophila follicle stem cells (FSC), neuroblasts and S2 cells. In ovaries, Tsh and Hedgehog (Hh) are co-expressed in the terminal filament and cap cells. The characterisation of a new tsh mutation causing female sterility allowed us to show that Tsh acts via Hh-mediated signalling pathway to control FSC proliferation. In this tsh background, the hsGal4 driven expression of tsh or hh partially rescues the abnormal phenotype allowing oogenesis progression. Furthermore, tsh overexpression mimics the hh overexpression associated phenotype. In neuroblasts, mutant tsh alleles are unable to exit mitosis. The phenotypes of double mutants with rod or bub1 resemble the tsh single mutant phenotype, suggesting failure to escape mitosis. Finally, tsh depletion in S2 cells mimics the tsh mutant phenotype in neuroblasts. We propose that during oogenesis, tsh affects FSC proliferation mediating Hh expression. In neuroblasts, tsh may also acts through Hh signalling, since expression of interference hedgehog, was severely downregulated in our DNA microarray analysis.
Edité par LAP LAMBERT Academic Publishing, 2012
ISBN 10 : 3848428504ISBN 13 : 9783848428502
Vendeur : PBShop.store UK, Fairford, GLOS, Royaume-Uni
Livre impression à la demande
PAP. Etat : New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Edité par LAP LAMBERT Academic Publishing, 2012
ISBN 10 : 3848428504ISBN 13 : 9783848428502
Vendeur : Mispah books, Redhill, SURRE, Royaume-Uni
Livre
Paperback. Etat : Like New. Like New. book.