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Validity of oral fluid for detection of HCV among Egyptian children: Detection of HCV in saliva of Egyptian children - Couverture souple

 
9783659136658: Validity of oral fluid for detection of HCV among Egyptian children: Detection of HCV in saliva of Egyptian children
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Présentation de l'éditeur :
This study aimed to Assess the prevalence of HCV infection among high risk group of Egyptian children and Evaluate the detection of HCV antibodies (anti-HCV) and HCV RNA in saliva against their detection in serum among HCV positive children.This study included 200 children (92 males and 108 females) who were attendants of Haematology Clinic at Abu El-Reish Hospital, Cairo University, for receiving frequent blood transfusions. Serum and saliva samples were analyzed for detection of anti-HCV by ELISA technique and for HCV RNA by a home made RT-PCR method. Liver function tests were performed also. Results of serum samples revealed that 134/200 (67%) children were anti-HCV seropositive, out of them 79/134 (59%) children had HCV RNA in their sera. Saliva samples of HCV infected children (n=79) showed that 53/79 (67.1%) and 31/79 (39.2%) were anti-HCV and HCV RNA positive respectively. Prevalence of HCV infection was 39.5% of 200 studied children. We can conclude that saliva could play a possible role of biological fluids as a non parenteral route of intrafamilial spread of HCV infection
Biographie de l'auteur :
Dr. Mariana Ghabrial has obtained her PhD degree in biochemistry in 2011.She worked in PCR lab at liver institute,Menofiya university.She is the auther of several articles published in reputed journals.

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Description du livre Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This study aimed to Assess the prevalence of HCV infection among high risk group of Egyptian children and Evaluate the detection of HCV antibodies (anti-HCV) and HCV RNA in saliva against their detection in serum among HCV positive children.This study included 200 children (92 males and 108 females) who were attendants of Haematology Clinic at Abu El-Reish Hospital, Cairo University, for receiving frequent blood transfusions. Serum and saliva samples were analyzed for detection of anti-HCV by ELISA technique and for HCV RNA by a home made RT-PCR method. Liver function tests were performed also. Results of serum samples revealed that 134/200 (67%) children were anti-HCV seropositive, out of them 79/134 (59%) children had HCV RNA in their sera. Saliva samples of HCV infected children (n=79) showed that 53/79 (67.1%) and 31/79 (39.2%) were anti-HCV and HCV RNA positive respectively. Prevalence of HCV infection was 39.5% of 200 studied children. We can conclude that saliva could play a possible role of biological fluids as a non parenteral route of intrafamilial spread of HCV infection 120 pp. Englisch. N° de réf. du vendeur 9783659136658

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Description du livre Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - This study aimed to Assess the prevalence of HCV infection among high risk group of Egyptian children and Evaluate the detection of HCV antibodies (anti-HCV) and HCV RNA in saliva against their detection in serum among HCV positive children.This study included 200 children (92 males and 108 females) who were attendants of Haematology Clinic at Abu El-Reish Hospital, Cairo University, for receiving frequent blood transfusions. Serum and saliva samples were analyzed for detection of anti-HCV by ELISA technique and for HCV RNA by a home made RT-PCR method. Liver function tests were performed also. Results of serum samples revealed that 134/200 (67%) children were anti-HCV seropositive, out of them 79/134 (59%) children had HCV RNA in their sera. Saliva samples of HCV infected children (n=79) showed that 53/79 (67.1%) and 31/79 (39.2%) were anti-HCV and HCV RNA positive respectively. Prevalence of HCV infection was 39.5% of 200 studied children. We can conclude that saliva could play a possible role of biological fluids as a non parenteral route of intrafamilial spread of HCV infection. N° de réf. du vendeur 9783659136658

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Description du livre Kartoniert / Broschiert. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Ghabrial MarianaDr. Mariana Ghabrial has obtained her PhD degree in biochemistry in 2011.She worked in PCR lab at liver institute,Menofiya university.She is the auther of several articles published in reputed journals.This study . N° de réf. du vendeur 5134093

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