Structural Biology Using Electrons and X-rays: An Introduction for Biologists - Couverture souple

Couverture souple

ISBN 10 : 0123705819 ISBN 13 : 9780123705815

Editeur : Academic Press, 2011

Synopsis

Structural Biology Using Electrons and X-rays is the perfect book to provide advanced undergraduates or graduate students with an accessible introduction to the two major diffraction-based techniques of structural biology. While concentrating on electron cryo-microscopy with image analysis, it also includes X-ray crystallography in a coherent survey of fundamental principles. Starting with Fourier transforms and progressing through optics and imaging principles, symmetry and three-dimensional reconstruction theory, Structural Biology Using Electrons and X-rays ends in an account of the latest methods adapted to crystals, helices, viral heads, and single particles.

A propos du livre

Présentation de l'éditeur

Structural Biology Using Electrons and X-Rays discusses the diffraction and image-based methods used for the determination of complex biological macromolecules. The book focuses on the Fourier transform theory, which is a mathematical function that is computed to transform signals between time and frequency domain. Composed of five parts, the book examines the development of nuclear magnetic resonance (NMR), which allows the calculation of the images of a certain protein. Parts 1 to 4 provide the basic information and the applications of Fourier transforms, as well as the different methods used for image processing using X-ray crystallography and the analysis of electron micrographs. Part 5 focuses entirely on the mathematical aspect of Fourier transforms. In addition, the book examines detailed structural analyses of a specimen’s symmetry (i.e., crystals, helices, polyhedral viruses and asymmetrical particles).

This book is intended for the biologist or biochemist who is interested in different methods and techniques for calculating the images of proteins using nuclear magnetic resonance (NMR). It is also suitable for readers without a background in physical chemistry or mathematics.

• Emphasis on common principles underlying all diffraction-based methods
• Thorough grounding in theory requires understanding of only simple algebra
• Visual representations and explanations of challenging content
• Mathematical detail offered in short-course form to parallel the text

Détails de l'édition

• Éditeur: Academic Press
• Date d'édition: 2011
• Langue: anglais
• ISBN 10: 0123705819
• ISBN 13: 9780123705815
• Reliure: Broché
• Nombre de pages: 450
• Éditeur: Moody Michael F.
• Coordonnées du fabricant: non disponible
• Personne responsable: Yeepin GmbH; 492000000000; sunshine12232@outlook.com; ; Alleestr.11; Kaiserslautern; Rheinland-Pfalz; 67655; Allemagne