Microarray Technology in Practice - Couverture souple

Russell, Steve; Meadows, Lisa A.; Russell, Roslin R.

 
9780123725165: Microarray Technology in Practice
Couverture souple
ISBN 10 : 012372516X ISBN 13 : 9780123725165
Editeur : Academic Press Inc, 2008

Synopsis

Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large-scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain daunting to many researchers. This guide is designed to demystify the technology and inform more biologists about this critically important experimental technique.

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Présentation de l'éditeur

Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large-scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain daunting to many researchers. This guide is designed to demystify the technology and inform more biologists about this critically important experimental technique.

  • Cohesive overview of the technology and available platforms, followed by detailed discussion of experimental design and analysis of microarray experiments

  • Up-to-date description of normalization methods and current methods for sample amplification and labeling

  • Deep focus on oligonucleotide design, printing, labeling and hybridization, data acquisition, normalization, and meta-analysis

  • Additional uses of microarray technology such as ChIP (chromatin immunoprecipitation) with hybridization to DNA arrays, microarray-based comparative genomic hybridization (CGH), and cell and tissue arrays

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Academic Press Inc
Date d'édition
2008
Langue
anglais
ISBN 10 
012372516X
ISBN 13 
9780123725165
Reliure
Broché
Nombre de pages
464
Coordonnées du fabricant
non disponible
Personne responsable
Yeepin GmbH
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