Cancer Immunotherapy: Immune Suppression and Tumor Growth - Couverture rigide

Couverture rigide

ISBN 10 : 0123942969 ISBN 13 : 9780123942968

Editeur : Academic Press Inc, 2013

Synopsis

There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumor immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers with an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease.

A propos du livre

À propos de l'auteur

Dr. Prendergast is an international leader in basic and preclinical biomedical research, with deep expertise in the discovery and development of molecular therapies for cancer and other chronic diseases. A scientist and inventor, he is widely recognized for translating laboratory discoveries into practical medical innovations and for founding and advising multiple biomedical startup companies. He has led major advances in cancer immunotherapy, including pioneering work on IDO inhibition and the development of cryoimmune vaccination strategies to address drug‑resistant metastatic disease. Formerly Editor‑in‑Chief of Cancer Research, he has played a significant role in shaping the field’s scientific direction. As President and CEO of LIMR, Dr. Prendergast established the acapreneurial™ model, integrating nonprofit research with entrepreneurial biotechnologies to accelerate clinical impact, societal benefit, and sustainable innovation.

Détails de l'édition

• Éditeur: Academic Press Inc
• Date d'édition: 2013
• Langue: anglais
• ISBN 10: 0123942969
• ISBN 13: 9780123942968
• Reliure: Relié
• Numéro d'édition: 2
• Nombre de pages: 684
• Éditeur: Prendergast George C., Jaffee Elizabeth M.
• Coordonnées du fabricant: non disponible
• Personne responsable: Yeepin GmbH; 492000000000; sunshine12232@outlook.com; ; Alleestr.11; Kaiserslautern; Rheinland-Pfalz; 67655; Allemagne