Chemical Modulators of Protein Misfolding and Neurodegenerative Disease - Couverture rigide

Seneci, Pierfausto

Couverture rigide

ISBN 10 : 0128019441 ISBN 13 : 9780128019443

Editeur : Academic Press Inc, 2015

Synopsis

This book is a neurochemistry-based companion for Protein Misfolding and Neurodegenerative Diseases: Molecular Targets, an Elsevier title by the same author publishing in December 2014. While the first book focuses on biology and molecular targets, this companion book describes how these targets are regulated by small molecules and disease-modifying compounds. The book begins with a brief introduction to how key proteins become dysfunctional, and each subsequent chapter describes major disease mechanisms in Alzheimer's and other tauopathies. Properties and development status of these molecular targets and disease mechanisms are thoroughly described, as are small molecule effectors of autophagy and dis-aggregating agents.

A propos du livre

À propos de l'auteur

Dr. Pierfausto Seneci is Associate Professor in the Department of Organic and Industrial Chemistry at the University of Milan. He is currently affiliated with the University of Milan Centre for Interdisciplinary Biomolecular Studies and Industrial Applications (CISI) Centre of Excellence, and is responsible for the Combinatorial Chemistry/High Throughput MedChem Laboratory. He has over 20 years of medicinal chemistry experience working in industry, and held business development positions with GSK, Sanofi, and start-up pharmaceutical companies including Sirenade and NiKem working in drug discovery, neurodegeneration, oncology, and antibacterials. He is author of approximately 80 papers on the topic and several book chapters, including the book "Solid-Phase Synthesis and Combinatorial Technologies" with Wiley-Interscience in 2000.

Détails de l'édition

• Éditeur: Academic Press Inc
• Date d'édition: 2015
• Langue: anglais
• ISBN 10: 0128019441
• ISBN 13: 9780128019443
• Reliure: Relié
• Numéro d'édition: 1
• Nombre de pages: 260
• Coordonnées du fabricant: non disponible
• Personne responsable: Yeepin GmbH; 492000000000; sunshine12232@outlook.com; ; Alleestr.11; Kaiserslautern; Rheinland-Pfalz; 67655; Allemagne