Drug Discovery in Cancer Epigenetics - Couverture rigide

Couverture rigide

ISBN 10 : 0128022086 ISBN 13 : 9780128022085

Editeur : Academic Press Inc, 2016

Synopsis

Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy prediction. Most importantly, epigenetic modifications are reversible and epigenetic players are found mutated in different cancers; therefore, they provide attractive therapeutic targets. There has been great interest in developing and testing epigenetic drugs, which inhibit DNA methyltransferases, histone modifying enzymes or chromatin reader proteins. The first few drugs are already FDA approved and have made their way into clinical settings. This book provides a comprehensive summary of the epigenetic drugs currently available and aims to increase awareness in this area to foster more rapid translation of epigenetic drugs into the clinic.

A propos du livre

À propos des auteurs

Dr. Gerda Egger is an Associate Professor of Epigenetics at the Clinical Institute of Pathology, Medical University of Vienna.

Dr. Paola Barbara Arimondo is the Director of the Unité de Service et de Recherche (USR n°3388) entitled "Epigenetic Targeting of Cancer -ETaC-" which brings together basic and applied research - a joint laboratory of the Institut de Recherche Pierre Fabre (IRPF) and the CNRS. She is extremely experienced in researching regulatory pharmaceuticals and cancer epigenetics.

Détails de l'édition

• Éditeur: Academic Press Inc
• Date d'édition: 2016
• Langue: anglais
• ISBN 10: 0128022086
• ISBN 13: 9780128022085
• Reliure: Relié
• Nombre de pages: 498
• Éditeur: Egger Gerda, Arimondo Paola
• Coordonnées du fabricant: non disponible
• Personne responsable: Yeepin GmbH; 492000000000; sunshine12232@outlook.com; ; Alleestr.11; Kaiserslautern; Rheinland-Pfalz; 67655; Allemagne