Adverse Events and Oncotargeted Kinase Inhibitors - Couverture rigide

Tridente, Giuseppe

Couverture rigide

ISBN 10 : 0128094001 ISBN 13 : 9780128094006

Editeur : Academic Press Inc, 2017

Synopsis

Adverse Events and Oncotargeted Kinase Inhibitors gathers and evaluates data on adverse events associated with tyrosine kinase inhibitors (TKIs), a powerful anti-tumor drug class that has recently been introduced for human therapy. This book compiles a comprehensive safety profile of each TKI from experiences in official therapeutic indications, also exploring off-label exploratory investigations and postmarketing pharmaceutical surveillance databases.

A brief history of each drug's development and submission is provided, along with a more detailed analysis of the mechanism(s) of action involved in therapeutic activity or related to the insurgence of specific adverse events. Early chapters focus on general characteristics of TKIs, typology, and classification of adverse events, while the final chapters analyze TKIs as AE inducers and classes of AEs by system or organ involvement.

This comprehensive resource compiles and critically reviews all of the relevant safety data for this class of drugs, with the goal of improving the understanding of pathogenesis and facilitating the prevention, monitoring, and management of these adverse events.

A propos du livre

À propos de l'auteur

Professor Emeritus of Immunology and Pathology

School of Medicine and Surgery

Coordinator of the Teachers' Committee for the Master in Translational Biomedicine

Universita degli Studi di Verona, Italy

Détails de l'édition

• Éditeur: Academic Press Inc
• Date d'édition: 2017
• Langue: anglais
• ISBN 10: 0128094001
• ISBN 13: 9780128094006
• Reliure: Relié
• Nombre de pages: 736
• Coordonnées du fabricant: non disponible
• Personne responsable: Yeepin GmbH; 492000000000; sunshine12232@outlook.com; ; Alleestr.11; Kaiserslautern; Rheinland-Pfalz; 67655; Allemagne