Second Generation Cell and Gene-Based Therapies: Biological Advances, Clinical Outcomes and Strategies for Capitalisation - Couverture rigide

Couverture rigide

ISBN 10 : 0128120347 ISBN 13 : 9780128120347

Editeur : Academic Press Inc, 2020

Synopsis

Second Generation Cell and Gene-Based Therapies: Biological Advances, Clinical Outcomes, and Strategies for Capitalisation serves as the only volume to the market to bridge basic science, clinical therapy, technology development, and business in the field of cellular therapy/cytotherapy. After more than two decades of painstaking fundamental research, the concept of therapeutic cells (stem cells, genes, etc.), beyond the concept of vaccines, is reaching clinical trial, with mounting confidence in the safety and efficacy of these products. Nonetheless, numerous incremental technical advances remain to be achieved. Thus, this volume highlights the possible R&D paths, which will ultimately facilitate clinical delivery of cutting edge curative products.The next waves of innovation are reviewed in depth for hematopoietic stem cells, mesenchymal stem cells, tissue engineering, CAR-T cells, and cells of the immune system, as well as for enabling technologies such as gene and genome editing. Additionally, deep dives in product fundamentals, history of science, pathobiology of diseases, scientific and technological bases, and financing and technology adoption constraints are taken to unravel what will shape the cytotherapy industry to the horizon 2025 and beyond. The outcome is not simply a scientific book, but a global perspective on the nascent field combining science, business, and strategic fundamentals.

A propos du livre

À propos des auteurs

University of Illinois at Urbana-Champaign, Institut Pasteur Paris, and University of Lille Flanders-Artois

- Sloan Fellow from London Business School and a microbiologist by training (University of Illinois at Urbana-Champaign, Institut Pasteur Paris, and University of Lille Flandres-Artois).

- Consulting, Partnering & Fund Raising, Founder, Managing Director, NxR Biotechnologies, Switzerland.

- Dr. Vertès is a strategy and business development consultant for cell therapeutic biotech companies, and works to enable seed funding in the field. Focusing on technology deployment and innovation commercialization, he has contributed to both industrial and pharmaceutical biotechnology, in different functions including research, manufacturing, contract research, and strategic alliances in pharmaceuticals (Lilly, Pfizer, Roche).

- Championed radical innovation for bringing to patients disease-modifying, paradigm-changing therapeutics such as siRNA, and led in a scientific and business manner Roche's global cell therapeutics strategy and implementation team resulting in Roche's entry in 2010 in the field of regenerative medicine.

- Member, Industry Committee-Europe, Tissue Engineering and Regenerative Medicine International Society

- Co-Editor, Stem Cells in Regenerative Medicine: Science, Regulation and Business Strategies (Wiley, 2015).

- Head of Operations & Strategy, Medicinal Sciences Division of R&D, Pfizer Inc.

- Responsible for all cell & gene therapy products, as well as previously developing Pfizer's Regenerative Medicine program.

- PhD in Genetics from Harvard Medical School.

- Adjunct faculty member at Northeastern University.

Research Chemical/Biochemical Engineer, United States Department of Agriculture (USDA), Agricultural Research Service (ARS), National Center for Agricultural Utilization Research (NCAUR), Peoria, IL, USA.
PhD (Chemical/Biological Engineering), PhD (Fermentation Technology)
Fellow in American Institute of Chemical Engineers (AIChE), Society for Industrial Microbiology & Biotechnology (SIMB), and American Institute of Chemists (AIC).
Co-Editor, Stem cells in Regenerative Medicine (Wiley, 2015)

Détails de l'édition

• Éditeur: Academic Press Inc
• Date d'édition: 2020
• Langue: anglais
• ISBN 10: 0128120347
• ISBN 13: 9780128120347
• Reliure: Relié
• Nombre de pages: 846
• Éditeur: Vertes Alain, Dowden Nathan J., Smith Devyn, Qureshi Nasib
• Coordonnées du fabricant: non disponible
• Personne responsable: Yeepin GmbH; 492000000000; sunshine12232@outlook.com; ; Alleestr.11; Kaiserslautern; Rheinland-Pfalz; 67655; Allemagne