Gpcr Signaling in Cancer - Couverture rigide

Couverture rigide

ISBN 10 : 0128202300 ISBN 13 : 9780128202302

Editeur : Academic Press Inc, 2020

Synopsis

GPCR Signaling in Cancer, Volume 145, the latest release in the Advances in Cancer Research series, highlights recent developments in the area of GPCRs and cancer biology. Chapters included in this volume cover several GPCRs and their downstream effectors as case examples to highlight their fundamental understanding and therapeutic potential. Specific chapters address the Role of GRKs and beta-arrestins in cancer, Atypical GPCRs in cancer, the Role of a chemokine receptor (CCR) 5 in cancer, Targeting G protein-coupled receptors for therapeutics in cancer, Emerging GPCR signaling pathways in cancer, and more.

G protein-coupled receptors (GPCRs) constitute a large family of cell surface receptors which are involved in nearly every cellular and physiological event. These receptors can recognize a broad array of ligands and they are targeted by nearly one third of the currently prescribed drugs including anti-cancer therapeutics.

A propos du livre

À propos de l?auteur

Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla's research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.

Détails de l'édition

• Éditeur: Academic Press Inc
• Date d'édition: 2020
• ISBN 10: 0128202300
• ISBN 13: 9780128202302
• Reliure: Relié
• Langue: anglais
• Nombre de pages: 164
• Éditeur: Shukla Arun K.
• Coordonnées du fabricant: non disponible