Investigating the Human Genome: Insights into Human Variation and Disease Susceptibility - Couverture rigide

Smith, Moyra

Couverture rigide

ISBN 10 : 0132168146 ISBN 13 : 9780132168144

Editeur : Financial TImes Prentice Hall, 2011

Synopsis

Leading medical genetics scholar Moyra Smith reviews current and recent work in genetics and genomics to assess progress in understanding human variation and the pathogenesis of common and rare diseases in which genetics plays a role. Smith provides an exceptional overview of the most important biomedical progress arising from the greatly increased genetic information base generated by gene mapping and the sequencing of the complete Human Genome.

 

This book addresses into a wide spectrum of topics associated with human genetics and genomics, including:

• Human origins; migrations and human population diversity gained though genomic analyses.
• The complexities of psychiatric diseases that are influenced by genetics.
• The pathogenesis of late-onset neurological diseases such as Alzheimer’s, Parkinsonism, and ALS.
• Key aspects of protein misfolding.
• Gene-environment interactions in DNA damage and repair and DNA instability.
• Micro RNAs and mRNA translation.
• Epigenetics.
• New functions for old enzymes in cancer.

A propos du livre

À propos de l?auteur

Moyra Smith is Professor of Pediatrics and Human Genetics at the School of Medicine at University of California, Irvine. A leading scholar in her field, she has served as an editor of McKusick’s classic “Red Book,” Mendelian Inheritance in Man. Smith’s monographs in the Oxford Series on Human Genetics include Mental Retardation and Developmental Delay: Genetic and Epigenetic Factors (2005), Translational Research in Genetics and Genomics (2008), and Phenotypic Variation: Exploration and Functional Genomics (2011).

Détails de l'édition

• Éditeur: Financial TImes Prentice Hall
• Date d'édition: 2011
• Langue: anglais
• ISBN 10: 0132168146
• ISBN 13: 9780132168144
• Reliure: Relié
• Nombre de pages: 224
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible