Two-Dimensional DNA Typing: A Parallel Approach to Genome Analysis - Couverture rigide

Uitterlinden, Andre G.; Vijg, Jan

Couverture rigide

ISBN 10 : 0137914504 ISBN 13 : 9780137914500

Editeur : Pearson Education Limited, 1994

Synopsis

This book focuses on a recently developed form of DNA analysis, which is based on a combination of two independent gel electrophoretic separation principles. In describing the technology on which the two-dimensional DNA separation principle is based, and in looking at its possible applications, this book is at the forefront of this rapidly emerging area.

A propos du livre

Présentation de l'éditeur

New technology for analyzing complex genomes is an important area of modern molecular biosciences. This book focuses on a recently developed genome scanning method, termed two-dimensional 2-D DNA typing, which is based on a combination of two independent electrophoretic separation principles. When separation according to size is coupled to separation according to base-pair composition, complex genomes can be resolved in a number of DNA fragments. These fragments or subsets can be visualized, for example, by hybridization analysis with specific probes. Genome scanning by 2-D DNA typing finds applications in many areas, such as linkage and association studies for identifying genetic traits in humans, animals and plants, studies on genetic instabilities in cancers, classification studies in bacteria and other lower organisms, studies on human mutation rates, and the identification of mutations in large genes.

Détails de l'édition

• Éditeur: Pearson Education Limited
• Date d'édition: 1994
• Langue: anglais
• ISBN 10: 0137914504
• ISBN 13: 9780137914500
• Reliure: Relié
• Nombre de pages: 220
• Coordonnées du fabricant: non disponible
• Personne responsable: Riccardo Bacigalupo; riccardo.bacigalupo@sanoma.it; ; Sanoma Italia Via Arconati, 1 �; Milano; 20135; Italie