Design of Enzyme Inhibitors As Drugs - Couverture rigide

Sandler, Merton

Couverture rigide

ISBN 10 : 0192615378 ISBN 13 : 9780192615374

Editeur : Oxford University Press, 1989

Synopsis

A collection of essays, based on research exploring ways in which the inhibition of the action of particular enzymes in the body can produce a desired therapeutic effect. The book contains accounts of the major target enzymes and their inhibitors which are currently the focus of research. The introductory chapters describe the underlying physical and chemical processes of enzyme inhibition and the general principles of inhibitor design using the many sophisticated and computer-based techniques that are now available. Subsequent chapters discuss in detail the wide range of individual target enzymes and inhibitors which are either in clinical use or are under study, emphasizing the factors which affect their usefulness in the clinical context - bioavailability, pharmaco kinetics and side-effects.

Détails de l'édition

• Éditeur: Oxford University Press
• Date d'édition: 1989
• Langue: anglais
• ISBN 10: 0192615378
• ISBN 13: 9780192615374
• Reliure: Relié
• Nombre de pages: 828
• Coordonnées du fabricant: non disponible
• Personne responsable: Messaggerie Libri; ufficio.anagrafiche@meli.it; ; Via Verdi, 8; Assago Milano; Italie