Articles liés à Brain Development: Normal Processes And the Effects...

Brain Development: Normal Processes And the Effects of Alcohol And Nicotine - Couverture rigide

 
9780195183139: Brain Development: Normal Processes And the Effects of Alcohol And Nicotine
Couverture rigide
ISBN 10 : 0195183134 ISBN 13 : 9780195183139
Editeur : Oxford University Press Inc, 2006

Synopsis

This is the first book about both normal development of the nervous system and how early exposure to alcohol and nicotine interferes with this development. The developing nervous system is highly dynamic and vulnerable to genetic and epigenetic factors that can be additive or synergistic. Disruption of normal brain development leads to an array of developmental disorders. One of the most common of these is mental retardation, the prime cause of which is prenatal exposure to alcohol. As chapters in this book show, alcohol has direct effects on the developing neural system and it affects genetic regulation. Another common neurotoxin is nicotine, and it is discussed in this book for three reasons: (1) the number of adolescents who smoke cigarettes is rising in some populations; (2) prenatal exposure to nicotine affects neurotransmitter systems that are critical for normal brain development and cognition; and (3) prenatal exposure to nicotine is often accompanied by prenatal exposure to alcohol.
The mature brain is the culmination of an orderly sequence of basic ontogenetic processes - cell proliferation, migration, differentiation, and death. Neural stem cells and progenitors proliferate in discreet sites; then, young neurons migrate long distances to their residences where they form neural networks. During this sequence many immature cells die, presumably eliminating unsuitable or non-competitive cells. Each process is regulated by genetic and environmental factors. When this regulation goes awry, a dysmorphic and dysfunctinoal brain results. Though this can be tragic in clinical settings, in experimental contexts it provides keen insight into normal brain development.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

This is the first book about both normal development of the nervous system and how early exposure to alcohol and nicotine interferes with this development. The developing nervous system is highly dynamic and vulnerable to genetic and epigenetic factors that can be additive or synergistic. Disruption of normal brain development leads to an array of developmental disorders. One of the most common of these is mental retardation, the prime cause of which is prenatal exposure to alcohol. As chapters in this book show, alcohol has direct effects on the developing neural system and it affects genetic regulation. Another common neurotoxin is nicotine, and it is discussed in this book for three reasons: (1) the number of adolescents who smoke cigarettes is rising in some populations; (2) prenatal exposure to nicotine affects neurotransmitter systems that are critical for normal brain development and cognition; and (3) prenatal exposure to nicotine is often accompanied by prenatal exposure to alcohol. The mature brain is the culmination of an orderly sequence of basic ontogenetic processes - cell proliferation, migration, differentiation, and death. Neural stem cells and progenitors proliferate in discreet sites; then, young neurons migrate long distances to their residences where they form neural networks. During this sequence many immature cells die, presumably eliminating unsuitable or non-competitive cells. Each process is regulated by genetic and environmental factors. When this regulation goes awry, a dysmorphic and dysfunctinoal brain results. Though this can be tragic in clinical settings, in experimental contexts it provides keen insight into normal brain development.

Revue de presse

...a very detailed and in-depth look at the topic...an excellent book that will be useful to many readers, including pediatricians, toxicologist, substance abuse specialists, researchers, and many others. (Doody's Notes)

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Oxford University Press Inc
Date d'édition
2006
Langue
anglais
ISBN 10 
0195183134
ISBN 13 
9780195183139
Reliure
Relié
Nombre de pages
424
Éditeur
Miller Michael W.
Coordonnées du fabricant
non disponible
Personne responsable
Ufficio Anagrafiche Messaggerie
ufficio.anagrafiche@meli.it

Via Verdi, 8
Assago Milano
20090
Italie