Matrix Metalloproteinases And T.I.M.P.s (Protein Profile) - Couverture souple

Woessner, J. Frederick

Couverture souple

ISBN 10 : 0198502680 ISBN 13 : 9780198502685

Editeur : Oxford University Press, U.S.A., 2005

Synopsis

The matrix metalloproteinases (M.M.P.s) are a large family of enzymes that breakdown different components of the extracellular matrix. Their catalytic activity is dependent a metal ion, usually zinc. This issue of the Protein Profiles covers the sequence information, three-dimensional structures, activation, protein substrates, specificity requirements, inhibition, and biological roles of all the currently identified M.M.P.s. The action of these enzymes must be carefully regulated. One way the cell does this, is by releasing inhibitory molecules known as tissue inhibitors of metalloproteinases (T.I.M.P.s). This volume contains information on the sequences, three-dimensional structures, and biological roles of the 4 known classes of T.I.M.P. . Matrix metalloproteinases will therefore be an invaluable source of data for all researchers interested in M.M.P.s and T.I.M.P.s.

A propos du livre

Présentation de l'éditeur

The matrix metalloproteinases (MMPs) are a large family of enzymes that break down different components of the extracellular matrix. Their catalytic activity is dependent on the metal ion zinc. This issue of the Protein Profiles covers the sequence information, three-dimensional structures, activation, protein substrates, specificity requirements, inhibition, and biological roles of all the currently identified MMPs. The action of these enzymes must be carefully regulated. One way the cell does this is by releasing inhibitory molecules known as tissue inhibitors of metalloproteinases (TIMPs). This volume contains information on the sequences, three-dimensional structures, and biological roles of the four known TIMPs. Matrix metalloproteinases and TIMPs will therefore be an invaluable source of data for all researchers interested in MMPs and TIMPS.

Biographie de l'auteur

Fred Woessner is at University of Kansas Medical Center. Hideaki Nagase is at University of Miami School of Medicine.

Détails de l'édition

• Éditeur: Oxford University Press, U.S.A.
• Date d'édition: 2005
• Langue: anglais
• ISBN 10: 0198502680
• ISBN 13: 9780198502685
• Reliure: Broché
• Nombre de pages: 240
• Coordonnées du fabricant: non disponible
• Personne responsable: Ufficio Anagrafiche Messaggerie; ufficio.anagrafiche@meli.it; ; Via Verdi, 8; Assago Milano; 20090; Italie