Gene Genealogies, Variation And Evolution: A Primer in Coalescent Theory - Couverture souple

Hein, Jotun

Couverture souple

ISBN 10 : 0198529961 ISBN 13 : 9780198529965

Editeur : Oxford University Press, U.S.A., 2005

Synopsis

Coalescent theory tells us what gene genealogies are expected to look like if populations have different demographic histories - i.e, population size, structure, etc. The aim of this book is to provide an accessible introduction to Coalescent Theory with a view towards data analysis. Coalescent Theory has in the last two decades moved from being an obscure technique that appealed to mathematical population geneticists to a central tool in data analysis of D.N.A. sequences. The completion of the sequencing of the human genome and accompanying determination of S.N.Ps and haplotypes will increase its importance even further. This textbook, rich in examples and illustrations, is suitable for a graduate course in statistics, population-, molecular-, and medical genetics.

A propos du livre

Revue de presse

This book fills a very important gap, as the first general textbook to deal exclusively with coalescent theory. (Systematic Biology)

this book should be mandatory reading for any graduate student working on population-level molecular data. (Evolution)

an excellent and timely book that should appeal to a variety of people in genetics and applied mathematics. (Professor Montgomery Slatkin (Berkeley))

the authors are outstanding experts in the field, and the book is topical and timely. (Professor David Balding (Imperial College))

Hein, Schierup and Wiuf have written the first general book on the coalescent. It is an engaging combination of clear mathematical derivation and real data examples. (Professor Joe Felsenstein (University of Washington))

There has been a dire need for a good book introducing coalescent theory to biologists. Gene Genealogies,Variation and Evolution fills this important gap this book should be mandatory reading for any graduate student working on population-level molecular data. (Evolution 60/1)

Présentation de l'éditeur

Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Rich in examples and illustrations it is ideal for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine, and for students studying the evolution of human population and disease. It is also an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia

Détails de l'édition

• Éditeur: Oxford University Press, U.S.A.
• Date d'édition: 2005
• Langue: anglais
• ISBN 10: 0198529961
• ISBN 13: 9780198529965
• Reliure: Broché
• Nombre de pages: 292
• Coordonnées du fabricant: non disponible
• Personne responsable: Ufficio Anagrafiche Messaggerie; ufficio.anagrafiche@meli.it; ; Via Verdi, 8; Assago Milano; 20090; Italie