Bioinformatics is the collective name for a set of skills that has now become arguably one of the most important information-gathering and knowledge-building tools in current science research. The increase in the reliance upon bioinformatics in current research has made it essential for training in these skills to become an integral part of current science education. Introduction to Bioinformatics is a timely and much-needed textbook which provides an accessible and thorough introduction to a subject which has become a fundamental part of biological science today. As a pioneer of the use of bioinformatics techniques in research, Dr Lesk brings unrivalled experience and expertise to the study of this field. The aim of the book is to integrate an understanding of the biological background of bioinformatics with development of necessary computing skills. Without describing computer science or sophisticated programming skills in detail, the book supports and encourages the application of the many powerful computational tools of bioinformatics in a way that is both relevant to and stimulating for the reader. The book contains numerous problems and innovative Weblems (for Web-based Problems) to encourage students to engage with the subject and, with the accompanying web site, to develop a working understanding and appreciation of the power of bioinformatics as a research tool. Web site www oup.com/uk/best.textbooks/biochemistry/bioinf/ A logo in the text alerts the reader to check the web site for the full text of programs referred to in the book. The web site also has links related to the book's problems, the innovative Weblems (for Web-based Problems), to encourage students to engage with the subject and, with the web site, to develop a working understanding and appreciation of the power of bioinformatics as a research tool.
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Life in a post-genomic age has the promise to revolutionize our understanding of how our genes shape who we are, how our genome evolved, and how we function. There are new possibilities for an improved quality of life as we exploit new knowledge to design novel, more effective drugs. Central to these possibilities being realized is one of the most important information-gathering, data-mining, and knowledge-building tools in current research and healthcare development: bioinformatics. An Introduction to Bioinformatics introduces students to the immense power of bioinformatics as a set of scientific tools. The book explains how to access the data archives of genomes and proteins, and the kinds of questions these data and tools can answer: how to make inferences from the data archives, to make connections among them, and to derive useful and interesting predictions. Blending factual content with many opportunities for active learning, Introduction to Bioinformatics offers a truly reader-friendly way to get to grips with this subject, making it the ideal resource for anyone new to the field. Online Resource Centre: The Online Resource Centre features the following materials: For lecturers (password protected): · Figures from the book available to download, to facilitate lecture slide preparation For students: · Hyperlinked bibliography - online links to articles referenced in the book, encouraging student engagement with the primary literature · Links to PDB structures of all proteins cited in the book, to enable students to investigate the 3D structures of proteins in a visual, interactive way · Data from the book in computer-readable form, which is available for instant use to facilitate hands-on learning by the student - Guidance to help students answer problems from the text, to support and encourage self-directed learning
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