Articles liés à Animal Virus Pathogenesis: A Practical Approach
Synopsis
The study of animal virus pathogenesis - how viruses cause disease - is an important and rapidly developing area, especially so since the development of AIDS and the consequent increase in research activity. Viruses can cause disease in two distinct ways. They can alter the cell and damage it directly by shutting down its basic mechanisms or by producing toxins or by breaking the cell membrane. Alternatively the virus can alter a cell's function without destroying it, for instance, in the case of a nerve cell the virus may alter synthesis of neurotransmitters. In contrast to the stricken cells damaged by viral infection, in this second type of infection the cells appear normal when examined by physical means, e.g. microscopy, and by most biochemical assays, e.g. total cellular RNA. Understanding viral pathogenesis requires knowledge and use of techniques drawn from several disciplines from researchers working at the interface between virology and immunology. This volume charts the way that viral tropism, viral expression , and viral infectivity are assayed. It describes the identification of antiviral cytotoxic T cells, natural killer and free antibody responses. The final chapters deal with the latest methods for raising antipeptide antibodies and making vaccinia/viral cDNA for immunologic target recognition, tissue and whole animal in situ hybridization.
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Présentation de l'éditeur
The study of animal virus pathogenesis - how viruses cause disease - is an important and rapidly developing area, especially so since the development of AIDS and the consequent increase in research activity. Viruses can cause disease in two distinct ways. They can alter the cell and damage it directly by shutting down its basic mechanisms or by producing toxins or by breaking the cell membrane. Alternatively the virus can alter a cell's function without destroying it, for instance, in the case of a nerve cell the virus may alter synthesis of neurotransmitters. In contrast to the stricken cells damaged by viral infection, in this second type of infection the cells appear normal when examined by physical means, e.g. microscopy, and by most biochemical assays, e.g. total cellular RNA. Understanding viral pathogenesis requires knowledge and use of techniques drawn from several disciplines from researchers working at the interface between virology and immunology. This volume charts the way that viral tropism, viral expression , and viral infectivity are assayed. It describes the identification of antiviral cytotoxic T cells, natural killer and free antibody responses. The final chapters deal with the latest methods for raising antipeptide antibodies and making vaccinia/viral cDNA for immunologic target recognition, tissue and whole animal in situ hybridization.
Revue de presse
'a very useful methods book, with each chapter containing a clear and concise description of the various protocols' Anthony Nash, University of Cambridge, Tibtech, December 1991 (vol.9)
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Animal Virus Pathogenesis: A Practical Approach (Practical Approach Series)
Edité par
IRL Press, 1990
ISBN 10 : 0199631018
ISBN 13 : 9780199631018
Ancien ou d'occasion
Softcover
Vendeur : Ammareal, Morangis, France
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Softcover. Etat : Très bon. Ancien livre de bibliothèque avec équipements. Edition 1990. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Former library book. Edition 1990. Ammareal gives back up to 15% of this item's net price to charity organizations. N° de réf. du vendeur G-088-956
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Animal Virus Pathogenesis: A Practical Approach
Edité par
IRL Press at Oxford University press, Oxford New York Tokyo, 1990
ISBN 10 : 0199631018
ISBN 13 : 9780199631018
Ancien ou d'occasion
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Vendeur : TAIXTARCHIV Johannes Krings, Aachen, Allemagne
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Broschur. Etat : gut bis sehr gut. 174 Seiten. - (Gewicht: 400 Gramm) Ehemaliges Expl. der Ärztebibliothek eines namhaften Forschungsinstituts; Etikett auf Cover belassen (kann u.U.entfernt werden), Signatur/Stempel innen; keine weiteren Einträge im Textbereich (Fotos auf Wunsch/photos on demand) (Please ask for the correct shipping costs!). / Former library book; signs on cover/signs stamps inside; no further writings inside. Book in clean and good to very good condition. N° de réf. du vendeur 013565
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Animal Virus Pathogenesis: A Practical Approach (Practical Approach Series)
Edité par
IRL Press, 1990
ISBN 10 : 0199631018
ISBN 13 : 9780199631018
Ancien ou d'occasion
paperback
Vendeur : Mispah books, Redhill, SURRE, Royaume-Uni
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paperback. Etat : Very Good. Very Good. book. N° de réf. du vendeur ERICA82901996310185
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Animal Virus Pathogenesis: A Practical Approach
Edité par
Oxford University Press, 1990
ISBN 10 : 0199631018
ISBN 13 : 9780199631018
Ancien ou d'occasion
Couverture souple
Vendeur : OM Books, Sevilla, SE, Espagne
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Etat : Usado - bueno. N° de réf. du vendeur 9780199631018
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