Articles liés à The Biology and Clinical Applications of Interleukin-2

The Biology and Clinical Applications of Interleukin-2 - Couverture rigide

 
9780199631377: The Biology and Clinical Applications of Interleukin-2
Couverture rigide
ISBN 10 : 0199631379 ISBN 13 : 9780199631377
Editeur : Oxford University Press, 1990

Synopsis

This publication presents the proceedings of the international symposium held at the University of Sheffield in 1989. It provides an up-to-date account of many important aspects of interleukin-2 (IL-2), and its clinical application. The molecular structure of IL-2 and its receptor subunits provide a basis for understanding lymphocyte activation by IL-2 and the generation of effector cells capable of mediating cytotoxicity towards tumours. Researchers of international standing present authoritative views on the molecular aspects of cell signalling, allowing speculation of the in vivo pathways of activation likely to be important in determining clinical responses. Attention has focussed on the use of cytokines, particularly IL-2, for the treatment of cancer. The recent results from clinical trials using IL-2 and adoptive cellular therapy provide a clear account of the clinical progress, and of the problems encountered in attempting to improve the therapeutic benefit of IL-2. The importance of mechanisms which subverse IL-2 responses is also given.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Revue de presse

'All articles are fully illustrated and very extensively referenced. This book will be a valuable source of information for researchers, clinicians and students in the fields of immunology, pharmacology, oncology, biochemistry and molecular biology.'Drugs of Today

'This is a major update of the molecular biology of IL-2 and its receptor.' Aslib Book List, Vol.56, No.4, April 1991

'...the great virtue of this book is that it includes the most important findings on the basic as well as on the clinical aspects of IL-2. ...there is no doubt that researchers, clinicians and students in immunology or oncology will find this volume to be a valuable source of information relevant to the structure and function of IL-2, from both the research and clinical perspectives.' Molecular Immunology

'this book provides a useful guide to this interesting area of experimental cancer therapy, particularly for those clinicians and scientists who are not familiar with the field.' F. Balkwill, Imperial Cancer Research Fund, European Journal of Cancer, Vol. 28A, No. 4/5. 1992

Présentation de l'éditeur

This publication presents the proceedings of the international symposium held at the University of Sheffield in 1989. It provides an up-to-date account of many important aspects of interleukin-2 (IL-2), and its clinical application. The molecular structure of IL-2 and its receptor subunits provide a basis for understanding lymphocyte activation by IL-2 and the generation of effector cells capable of mediating cytotoxicity towards tumours. Researchers of international standing present authoritative views on the molecular aspects of cell signalling, allowing speculation of the in vivo pathways of activation likely to be important in determining clinical responses. Attention has focussed on the use of cytokines, particularly IL-2, for the treatment of cancer. The recent results from clinical trials using IL-2 and adoptive cellular therapy provide a clear account of the clinical progress, and of the problems encountered in attempting to improve the therapeutic benefit of IL-2. The importance of mechanisms which subverse IL-2 responses is also given.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Oxford University Press
Date d'édition
1990
Langue
anglais
ISBN 10 
0199631379
ISBN 13 
9780199631377
Reliure
Relié
Nombre de pages
200
Éditeur
Rees Robert C.
Coordonnées du fabricant
non disponible
Personne responsable
Ufficio Anagrafiche Messaggerie
ufficio.anagrafiche@meli.it

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