Protein Phosphorylation: A Practical Approach - Couverture rigide

Hardie, D. Grahame

Couverture rigide

ISBN 10 : 0199633061 ISBN 13 : 9780199633067

Editeur : Oxford University Press, 1993

Synopsis

Reversible phosphorylation is one of the major mechanisms by which protein activity is controlled in all eukaryotic cells. Networks of protein kinases and phosphatases, which catalyze phosphorylation and dephosphorylation respectively, are responsible for switching between different pathways of cell division, development or differentiation in response to hormones or growth factors. This book provides a comprehensive description of current methods for studying protein phosphorylation and the protein kinases and phosphatases which catalyze it. It includes detailed protocols for studying phosphorylation in intact cells, approaches using enzyme inhibitors, purification of serine/threonine-specific protein kinases/phosphatases, analysis of kinase/phosphatase specificity and cloning relevant cDNAs. It should be of interest to researchers in the fields of intracellular and intercellular signalling, including biochemists, molecular biologists and pharmacologists.

Détails de l'édition

• Éditeur: Oxford University Press
• Date d'édition: 1993
• Langue: anglais
• ISBN 10: 0199633061
• ISBN 13: 9780199633067
• Reliure: Relié
• Nombre de pages: 322
• Coordonnées du fabricant: non disponible
• Personne responsable: Messaggerie Libri; ufficio.anagrafiche@meli.it; ; Via Verdi, 8; Assago Milano; Italie