Protein Structure Prediction - Couverture souple

Sternberg, Michael J. E.

Couverture souple

ISBN 10 : 0199634963 ISBN 13 : 9780199634965

Editeur : Oxford University Press, USA, 1997

Synopsis

The prediction of the three-dimensional structure of a protein from its amino acid sequence is a problem faced by an increasing number of biological scientists. This book provides a practical guide to making these predictions by reviewing strategies of different computer modeling algorithms and highlighting the degree of confidence attributed to them. Also in the volume are descriptions of the following: the principles of protein folding; sequence homology and motif searches; prediction of secondary structure; homology modeling; modeling of antibody combining sites; tertiary fold recognition; modeling of transmembrane proteins; ab initio prediction; protein-ligand docking simulations; and the use of molecular mechanics and dynamics. both non-specialists who require guidance to identify and evaluate appropriate strategies and experts who require a contemporary view of the field, will find this volume a worthy addition to their research libraries.

A propos du livre

Présentation de l'éditeur

The three-dimensional structure of proteins is a key factor in their biological activity. There is an increasing need to be able to predict the structure of a protein once its amino-acid sequence is known; this book presents practical methods of achieving that ambitious aim, using the latest computer modelling algorithms.

Revue de presse

wide ranging and very well documented accounts of the many practical aspects and various areas of application. The book should be of practical value especially to geneticists and molecular biologists. (Aslib Book Guide, vol.62, no.7, July 1997)

Détails de l'édition

• Éditeur: Oxford University Press, USA
• Date d'édition: 1997
• Langue: anglais
• ISBN 10: 0199634963
• ISBN 13: 9780199634965
• Reliure: Broché
• Nombre de pages: 320
• Coordonnées du fabricant: non disponible
• Personne responsable: Ufficio Anagrafiche Messaggerie; ufficio.anagrafiche@meli.it; ; Via Verdi, 8; Assago Milano; 20090; Italie