Blockbuster Drugs: The Rise and Decline of the Pharmaceutical Industry - Couverture rigide

Li, Jie Jack

Couverture rigide

ISBN 10 : 0199737681 ISBN 13 : 9780199737680

Editeur : Oxford University Press Inc, 2014

Synopsis

Blockbuster drugs-each of which generates more than a billion dollars a year in revenue-have revolutionized the industry since the early 1980s, when sales of Tagamet alone transformed a minor Philadelphia-based firm into the world's ninth-largest pharmaceutical company. In Blockbuster Drugs, Jie Jack Li tells the fascinating stories behind the discovery and development of these highly lucrative medicines, while also exploring the tumult the industry now faces as the "patent cliff" nears.

Having spent most of his career in drug research and development, Li brings an insider's eye to the narrative as he recounts the tales of discovery behind such drugs as Tagamet, Zantac, Claritin, Prilosec, Nexium, Serouquel, Plavix, and Ambien. As he discusses each breakthrough, Li also shows that scientific research is filled with human drama-serendipitous discoveries, sudden insights, tense confrontations. For instance, the author tells of James Black, who persisted in the research that led to Tagamet-and that would ultimately win him a Nobel Prize-despite pressure from top executives to pursue "more profitable" work. The book shows how research behind Prilosec combined creativity, international cooperation, and luck-the turning point being a chance encounter of American and Swedish scientists at a conference in Uppsala. There are also tales of fabulous rewards--George Rieveschl, the chemist who invented Benadryl, made a fortune on royalties-and of unjust desserts. Finally, Li shows that for the world's largest prescription drug manufacturers, recent years have been harrowing, as many popular drugs have come off patent in the U.S. market, meaning hundreds of billions of dollars in lost revenue.

Anyone who enjoys tales of scientific discovery, or is curious about the history behind the prescriptions they take, or wants a revealing inside look at the pharmaceutical industry will find this book well worth reading.

A propos du livre

À propos de l'auteur

Jie Jack Li was a drug discovery chemist at Bristol-Myers Squibb Company. He is the author of Triumph of the Heart: The Story of Statins (Oxford, 2009), Modern Organic Synthesis in the Laboratory (Oxford, 2007), and Laughing Gas, Viagra, and Lipitor: The Human Stories Behind the Drugs We Use (Oxford, 2006).

Détails de l'édition

• Éditeur: Oxford University Press Inc
• Date d'édition: 2014
• Langue: anglais
• ISBN 10: 0199737681
• ISBN 13: 9780199737680
• Reliure: Relié
• Nombre de pages: 238
• Coordonnées du fabricant: non disponible
• Personne responsable: Ufficio Anagrafiche Messaggerie; ufficio.anagrafiche@meli.it; ; Via Verdi, 8; Assago Milano; 20090; Italie