Methodological Challenges in Biomedical HIV Prevention Trials - Couverture souple

Institute Of Medicine; Board On Global Health; Committee On The Methodological Challenges In HIV Prevention Trials

Couverture souple

ISBN 10 : 0309114306 ISBN 13 : 9780309114301

Editeur : National Academies Press, 2008

Synopsis

The number of people infected with HIV or living with AIDS is increasing at unprecedented rates as various scientists, organizations, and institutions search for innovative solutions to combating and preventing the disease. At the request of the Bill & Melinda Gates Foundation, Methodological Challenges in Biomedical HIV Prevention Trials addresses methodological challenges in late-stage nonvaccine biomedical HIV prevention trials with a specific focus on microbicide and pre-exposure prophylaxis trials. This book recommends a number of ways to improve the design, monitoring, and analysis of late-stage clinical trials that evaluate nonvaccine biomedical interventions. The objectives include identifying a beneficial method of intervention, enhancing quantification of the impact, properly assessing the effects of using such an intervention, and reducing biases that can lead to false positive trial results.

According to Methodological Challenges in Biomedical HIV Prevention Trials, the need to identify a range of effective, practical, and affordable preventive strategies is critical. Although a large number of promising new HIV prevention strategies and products are currently being tested in late-stage clinical trials, these trials face a myriad of methodological challenges that slow the pace of research and limit the ability to identify and fully evaluate effective biomedical interventions.

A propos du livre

À propos de l?auteur

Stephen W. Lagakos and Alicia R. Gable, Editors, Committee on the Methodological Challenges in HIV Prevention Trials

Détails de l'édition

• Éditeur: National Academies Press
• Date d'édition: 2008
• Langue: anglais
• ISBN 10: 0309114306
• ISBN 13: 9780309114301
• Reliure: Broché
• Numéro d'édition: 1
• Nombre de pages: 270
• Éditeur: Gable Alicia R., Lagakos Stephen W.
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible