Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of 'Linker Chemistry' in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding.
The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
Dr. Madan's major areas of research include Self-assembled Supramolecular systems viz. liposomes, niosomes, cyclodextrin, nano- & micro-particles and solid-lipid nanoparticles. The focus is centered onto the exploitation of US FDA approved biomaterials in combination with other potential lipids and polymers to develop the innovative dosage forms and drug delivery systems in order to improve the bioavailability, stability, safety (tolerance) and patient-compliance.
Whilst a wide range of applications are being taken up, the special emphasis is given to augment the aqueous solubility and bioavailability of lipophilic drugs.Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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