Statistics in Human Genetics - Couverture souple

Sham, Pak

 
9780340662410: Statistics in Human Genetics

Synopsis

In human genetic research, sophisticated statistical methods are increasingly being used to analyse results. Until now there has been no book to introduce and explain these methods. The methods are based on both biology and statistics and are likely to contribute to major scientific and medical advances in the next century. Topics include the estimation of allele frequencies, the testing for Hardy-Weinberg equilibrium, classical and complex segregation analysis, linkage analysis for Mendelian and complex diseases and quantitative traits, the detection of allelic associations, the estimation of heritability for multifactorial traits and path analysis. An understanding of elementary statistical concepts is assumed, but the objectives, principles and limitations of the methods are discussed in detail. The book will interest scientists engaged in human genetic research and advanced students of genetics and statistics.

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Présentation de l'éditeur

In human genetic research sophisticated statistical methods are increasingly being used to analyse results. Until now there has been no book to introduce and explain these methods. The methods are based on both biology and statistics and are likely to contribute to major scientific and medical advances in the next century. Topics include the estimation of allele frequencies, the testing for Hardy-Weinberg equilibrium, classical and complex segregation analysis, linkage analysis for Mendelian and complex diseases and quantitative traits, the detection of allelic associations, the estimation of heritability for multifactorial traits and path analysis. An understanding of elementary statistical concepts is assumed, but the objectives, principles and limitations of the methods are discussed in detail.

The book will interest scientists engaged in human genetic research and advanced students of genetics and statistics.

Revue de presse

... an extremely valuable introduction...invaluable to new researchers in human disease genetics.. (The Statistician, No. 47, 1998)

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Autres éditions populaires du même titre

9780470689288: Statistics in Human Genetics

Edition présentée

ISBN 10 :  0470689285 ISBN 13 :  9780470689288
Editeur : John Wiley & Sons, 2009
Couverture souple